Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.54 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556993 | 0.86 | SLC22A12 (0.54) | SLC16A3SLC22A12KMT2AMEN1IDH1 | |
| SCHEMBL3556820 | 0.85 | SLC16A3 (0.57) | SLC16A3LMNAPOLBHTR6PTK2B | |
| SCHEMBL3560333 | 0.83 | PTK2B (0.60) | SLC16A3LMNAKMT2AMEN1POLB | |
| SCHEMBL3555622 | 0.82 | SLC16A3 (0.72) | SLC16A3LIMK2LMNAMAPTKMT2A | |
| SCHEMBL3562430 | 0.79 | IDH1 (0.53) | SLC16A3SLC22A12MAPTKMT2AMEN1 | |
| SCHEMBL3555827 | 0.79 | PKLR (0.53) | SLC16A3SLC22A12KMT2AMEN1IDH1 | |
| SCHEMBL3560292 | 0.78 | PTK2B (0.50) | SLC16A3LIMK2LMNAHTR6PTK2B | |
| SCHEMBL3557793 | 0.78 | SLC16A3 (0.56) | SLC16A3LMNAKMT2AMEN1PTK2B | |
| SCHEMBL3562289 | 0.77 | MAPT (0.61) | SLC16A3LMNAMAPTKMT2AMEN1 | |
| SCHEMBL3720283 | 0.77 | SLC22A12 (0.62) | SLC22A12LMNAKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761486-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | Merck Patent GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| WO-2006000288-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | claimed |