SCHEMBL5165261

SCHEMBL5165261

Oc1cccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 3/20 0.41
LMNA P02545 2/20 0.41
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA5A P35218 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
KIF11 P52732 1/20 0.36
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
BAZ1A Q9NRL2 1/20 0.35
HSD17B1 P14061 4/20 0.34
HSD17B2 P37059 4/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28088551 0.92 ALDH1A1 (0.44) ALDH1A1CYP3A4LMNACA12CA2
SCHEMBL842514 0.84 CA12 (0.48) ALDH1A1CYP3A4LMNACA12CA2
SCHEMBL30887991 0.84 CA12 (0.48) ALDH1A1CYP3A4LMNACA12CA2
SCHEMBL21367600 0.83 PGK1 (0.40) ALDH1A1LMNACA2CA9CA5A
SCHEMBL28294124 0.80 ALDH1A1 (0.44) ALDH1A1CYP3A4LMNACA12CA2
SCHEMBL11584197 0.79 NR1H3 (0.42) HSD17B10MEN1KMT2ATSHRPGK1
SCHEMBL7966485 0.78 KCNN4 (0.43) CYP3A4LMNAKIF11NPC1RAB9A
SCHEMBL28294125 0.78 ALDH1A1 (0.42) ALDH1A1CYP3A4LMNACA12CA2
SCHEMBL15319724 0.77 TSHR (0.59) ALDH1A1CYP3A4LMNACA12CA2
SCHEMBL9651762 0.77 TSHR (0.59) ALDH1A1CYP3A4LMNACA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222237-B1 MATERIALS FOR INDUCING ALIGNMENT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ELSICON INC (US) 2007-04-11 EP disclosed
US-6713135-B2 BRANCHED POLYIMIDE, POLYAMIC ACIDS ELSICON, INC. 2004-03-30 US disclosed
EP-1222237-A4 MATERIALS FOR INDUCING ALIGNMENT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ELSICON INC (US) 2003-01-15 EP disclosed
EP-1222237-A1 MATERIALS FOR INDUCING ALIGNMENT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS Elsicon, Inc. (US) 2002-07-17 EP disclosed
US-6380432-B2 AROMATIC DIAMINES USEFUL IN PREPARING POLYIMIDES ELSICON INC. 2002-04-30 US disclosed
US-20010039361-A1 Materials for inducing alignment in liquid crystal and liquid crystal displays GIBBONS WAYNE M (US) 2001-11-08 US disclosed
US-20010018099-A1 Materials for inducing alignment in liquid crystals and liquid crystal displays ELSICON, INC. 2001-08-30 US disclosed
US-6242061-B1 POLYAMIC ACIDS, POLYIMIDES ELSICON INC. 2001-06-05 US disclosed
WO-2001030938-A1 MATERIALS FOR INDUCING ALIGNMENT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ELSICON, INC. (US) 2001-05-03 WO disclosed
US-6194039-B1 POLYIMIDES, POLYAMIC ACIDS ELSICON, INC. 2001-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010039361-A1 Materials for inducing alignment in liquid crystal and liquid crystal displays DYNC1LI1, DYNC1LI2, DYNLL1 ALDH1A1 1492/4885CYP3A4 3978/4885LMNA 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.