Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 10/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385421 | 0.84 | SLC1A1 (0.43) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| SCHEMBL8439242 | 0.83 | SLC7A5 (0.44) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| SCHEMBL6136549 | 0.82 | DPP4 (0.42) | DPP4DPP8DPP9 | |
| Serine SCHEMBL18694955 | 0.81 | SLC1A1 (0.39) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| SCHEMBL5707690 | 0.80 | SLC7A5 (0.48) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| SCHEMBL542821 | 0.80 | DPP4 (0.41) | DPP4DPP8DPP9 | |
| SCHEMBL27408566 | 0.80 | NAAA (0.37) | DPP4DPP8DPP9 | |
| SCHEMBL3930248 | 0.80 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL5161688 | 0.80 | DPP4 (0.46) | DPP4DPP8DPP9 | |
| SCHEMBL1537380 | 0.79 | DPP4 (0.40) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802661-A1 | MUTATED CEPHALOSPORIN HYDROXYLASE AND ITS APPLICATION IN DEACETYLCEPHALOSPORANIC ACID SYNTHESIS | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2014-11-19 | — | — | EP | disclosed |
| WO-2013105030-A1 | MUTATED CEPHALOSPORIN HYDROXYLASE AND ITS APPLICATION IN DEACETYLCEPHALOSPORANIC ACID SYNTHESIS | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2013-07-18 | — | — | WO | disclosed |
| CN-101198693-B | Variant forms of urate oxidase and use thereof | SAVIENT PHARMACEUTICALS INC | 2013-03-27 | — | — | CN | disclosed |
| EP-1646401-A4 | SPECIFIC HUMAN ANTIBODIES | BIO TECHNOLOGY GENERAL ISRAEL (IL) | 2007-07-18 | — | — | EP | disclosed |
| EP-1649001-A2 | ANTIBODIES AND USES THEREOF | Bio-Technology General (Israel) Ltd. (IL) | 2006-04-26 | — | — | EP | disclosed |
| EP-1646401-A2 | SPECIFIC HUMAN ANTIBODIES | Bio-Technology General (Israel) Ltd. (IL) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005010153-A2 | ANTIBODIES AND USES THEREOF | BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) | 2005-02-03 | — | — | WO | disclosed |
| WO-2005005455-A2 | SPECIFIC HUMAN ANTIBODIES | BIO-TECHNOLOGY GENERAL (ISRAEL)LTD. (IL) | 2005-01-20 | — | — | WO | disclosed |