Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5167710 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL8161627 | 0.78 | CYP11B1 (0.32) | CYP19A1CYP11B1CYP11B2DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL5165524 | 0.77 | CYP11B1 (0.32) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL438153 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5168249 | 0.74 | SLC6A2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5515983 | 0.73 | KDM4E (0.32) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL5415129 | 0.72 | BRD4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL1539640 | 0.71 | CYP11B1 (0.33) | CYP19A1CYP11B1CYP11B2DRD2DRD4 | |
| SCHEMBL6905138 | 0.71 | LMNA (0.32) | CYP19A1CYP11B1CYP11B2DRD2DRD4 | |
| SCHEMBL8149969 | 0.70 | LMNA (0.35) | CYP19A1CYP11B1CYP11B2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247686-B2 | Solid cocatalyst component for olefin polymerization and catalyst system thereof | BASELL POLYOLEFINE GMBH (DE) | 2007-07-24 | — | — | US | disclosed |
| EP-1442067-B1 | SOLID COCATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST SYSTEM THEREOF | SUNALLOMER LTD (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-7005398-B2 | Olefin polymerization catalyst, catalyst component for olefin polymerization, method of storing these, and process for producing olefin polymer | SUNALLOMER LTD. (JP) | 2006-02-28 | — | — | US | disclosed |
| US-20050009689-A1 | Solid cocatalyst component for olefin polymerization and catalyst system thereof | SUNALLOMER LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
| US-20040054102-A1 | Olefin polymerization catalyst, catalyst component for olefin polymerization, method of storing these, and process for producing olefin polymer | SUNALLOMER LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1359166-A1 | OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD OF STORING THESE, AND PROCESS FOR PRODUCING OLEFIN POLYMER | Sunallomer Ltd (JP) | 2003-11-05 | — | — | EP | disclosed |