SCHEMBL6905138

SCHEMBL6905138

CC1=Cc2ccccc2C1[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
ACHE P22303 1/20 0.32
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
HTR2A P28223 1/20 0.30
CYP19A1 P11511 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27602854 0.98 LMNA (0.31) LMNATSHRALOX12ACHE
SCHEMBL8149969 0.76 LMNA (0.35) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL251288 0.74 DRD2 (0.41) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL5090888 0.74 LMNA (0.33) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL29458545 0.74 DRD2 (0.41) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL813995 0.74 LMNA (0.33) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL8370739 0.74 TACR1 (0.32) LMNAALDH1A1DRD2DRD4
SCHEMBL7053946 0.74 CYP19A1 (0.32) LMNAALDH1A1CYP19A1CYP11B1CYP11B2
SCHEMBL12629758 0.73 MAOA (0.37) LMNATSHRALOX12ACHEALDH1A1
Iodide SCHEMBL1539721 0.73 LMNA (0.32) LMNATSHRALOX12ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110546171-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2023-02-28 CN disclosed
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
CN-110603274-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-09-30 CN disclosed
CN-110612315-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-26 CN disclosed
CN-110582518-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-09 CN disclosed
CN-114401977-A Transition metal compound and catalyst composition comprising the same 株式会社LG化学 2022-04-26 CN disclosed
CN-108026115-B Multi-head or double-head composition capable of being used for chain shuttling and preparation method thereof 陶氏环球技术有限责任公司 2021-11-09 CN disclosed
EP-3902871-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS Dow Global Technologies LLC (US) 2021-11-03 EP disclosed
EP-3902868-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS Dow Global Technologies LLC (US) 2021-11-03 EP disclosed
EP-3902867-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS Dow Global Technologies LLC (US) 2021-11-03 EP disclosed
CN-101331163-A Olefin block copolymers catalyzed by polymerizable shuttling agents DOW GLOBAL TECHNOLOGIES INC (US) 2008-12-24 CN disclosed
CN-1954005-A Catalyst composition comprising shuttling agent for ethylene multi-block copolymer formation DOW GLOBAL TECHNOLOGIES INC (US) 2007-04-25 CN disclosed
CN-1946748-A Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECH HOLDINGS CV (NL) 2007-04-11 CN disclosed
EP-1421375-A2 METHOD AND APPARATUS FOR DETERMINATION OF WATER AND FOR NORMAL PHASE LIQUID CHROMATOGRAPHY DOW GLOBAL TECHNOLOGIES INC. (US) 2004-05-26 EP disclosed
WO-2003019176-A2 METHOD AND APPARATUS FOR DETERMINATION OF WATER AND FOR NORMAL PHASE LIQUID CHROMATOGRAPHY DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-06 WO disclosed
EP-1189950-A1 SUPPORT CATALYST FOR OLEFIN POLYMERIZATION Basell Polyolefine GmbH (DE) 2002-03-27 EP disclosed
CN-1289343-A Improved olefin polymerization process DOW CHEMICAL CO (US) 2001-03-28 CN disclosed
WO-2000078823-A1 SUPPORT CATALYST FOR OLEFIN POLYMERIZATION BASELL POLYOLEFINE GMBH (DE) 2000-12-28 WO disclosed
US-5831105-A Process for preparing bridged metallocenes TARGOR GMBH (DE) 1998-11-03 US disclosed
US-5360921-A REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-11-01 US disclosed