SCHEMBL516573

SCHEMBL516573

OCCOc1ccccc1C1CCCCC1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 7/20 0.63
HTR1D P28221 2/20 0.57
HTR1B P28222 2/20 0.57
HTR1A P08908 6/20 0.49
SLC6A2 P23975 4/20 0.49
SLC6A4 P31645 4/20 0.49
CYP1A2 P05177 2/20 0.49
ADRA2A P08913 2/20 0.49
CYP2D6 P10635 2/20 0.49
ADRA1A P35348 2/20 0.49
USP2 O75604 1/20 0.49
CHRM1 P11229 1/20 0.49
CYP2C9 P11712 1/20 0.49
DRD1 P21728 1/20 0.49
TBXA2R P21731 1/20 0.49
PTGS1 P23219 1/20 0.49
OPRM1 P35372 1/20 0.49
DRD3 P35462 1/20 0.49
KCNH2 Q12809 1/20 0.49
PRMT5 O14744 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11373736 1.00 PTGDR2 (0.63) PTGDR2HTR1DHTR1BHTR1ASLC6A2
SCHEMBL7637813 0.98 PTGDR2 (0.60) PTGDR2HTR1DHTR1BHTR1ASLC6A2
SCHEMBL19248412 0.91 PTGDR2 (0.51) PTGDR2HTR1DHTR1BHTR1ASLC6A2
SCHEMBL15509990 0.91 PTGDR2 (0.51) PTGDR2HTR1DHTR1BHTR1ASLC6A2
SCHEMBL29386002 0.91 PTGDR2 (0.51) PTGDR2HTR1DHTR1BHTR1ASLC6A2
SCHEMBL29386397 0.89 PTGDR2 (0.50) PTGDR2HTR1DHTR1BHTR1ASLC6A2
SCHEMBL15509414 0.89 PTGDR2 (0.50) PTGDR2HTR1DHTR1BHTR1ASLC6A2
SCHEMBL11372543 0.83 PTGDR2 (0.63) PTGDR2HTR1DHTR1BHTR1ASLC6A2
Ethylene Glycol SCHEMBL6933704 0.83 PTGDR2 (0.58) PTGDR2HTR1DHTR1BHTR1ASLC6A2
SCHEMBL577696 0.80 SLC6A9 (0.44) PTGDR2HTR1DHTR1BSLC6A9PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111465589-B Compound having fluorene skeleton and method for producing same 帝人株式会社 2024-01-05 CN disclosed
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same TEIJIN LIMITED (JP) 2022-05-24 US disclosed
WO-2021006192-A1 THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE AND PRODUCT 三菱電機株式会社 2021-01-14 WO disclosed
EP-3747856-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME Teijin Limited (JP) 2020-12-09 EP disclosed
US-20200354517-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME TEIJIN LIMITED (JP) 2020-11-12 US disclosed
WO-2019151504-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF 帝人株式会社 2019-08-08 WO disclosed
EP-1243572-B1 PROCESS FOR THE PREPARATION OF CYCLOHEXANOL ASAHI CHEMICAL IND (JP) 2015-03-25 EP disclosed
US-8841491-B2 Method for producing fluorene derivative TAOKA CHEMICAL CO., LTD. (JP) 2014-09-23 US disclosed
EP-2420485-A1 METHOD FOR PRODUCING FLUORENE DERIVATIVE Taoka Chemical Co., Ltd. (JP) 2012-02-22 EP disclosed
US-20120029244-A1 METHOD FOR PRODUCING FLUORENE DERIVATIVE TAOKA CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
US-6552235-B2 Catalyzing hydration reaction of cyclohexene with water using a solid catalyst in a solvent to increase the yield ASAHI KASEI KABUSHIKI KAISHA (JP) 2003-04-22 US disclosed
US-20030018223-A1 Process for the preparation of cyclohexanol ASAHI KASEI KABUSHIKI KAISHA (JP) 2003-01-23 US disclosed
US-6476258-B1 Process for producing aryloxyacetic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-05 US disclosed
EP-1243572-A1 PROCESS FOR THE PREPARATION OF CYCLOHEXANOL Asahi Kasei Kabushiki Kaisha (JP) 2002-09-25 EP disclosed
EP-1067108-A2 Process for producing aryloxyacetic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354517-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME RFT1, AFF1, RER1 PTGDR2 1739/4885HTR1D 292/4885HTR1B 735/4885
US-20120029244-A1 METHOD FOR PRODUCING FLUORENE DERIVATIVE ADH1A, AFF2, AFF1 PTGDR2 390/4885HTR1D 2700/4885HTR1B 2889/4885
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same RFT1, AFF1, RER1 PTGDR2 1739/4885HTR1D 292/4885HTR1B 735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.