Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954788 | 0.85 | ABL1 (0.58) | ABL1BCRPRKCAPRKCDKMT2A | |
| SCHEMBL3952943 | 0.79 | IGF1R (0.72) | IGF1RFADS1KMT2AMEN1KDM4E | |
| SCHEMBL1701943 | 0.77 | RAB9A (0.58) | IGF1RKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL7142310 | 0.74 | MAP3K5 (0.61) | IGF1RABL1BCRPRKCAPRKCD | |
| Diphenylamine SCHEMBL28251107 | 0.74 | ALDH1A1 (0.71) | PRKCDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4187426 | 0.73 | ABL1 (0.60) | ABL1BCRPRKCAPRKCDKMT2A | |
| SCHEMBL3951245 | 0.72 | HDAC6 (0.58) | IGF1RABL1BCRPRKCAPRKCD | |
| Quinoline SCHEMBL27865896 | 0.72 | ALDH1A1 (0.74) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL4738631 | 0.71 | FADS1 (0.83) | FADS1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL22109526 | 0.71 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789393-A2 | PYRIDINYLAMINES | GPC Biotech AG (DE) | 2007-05-30 | — | — | EP | claimed |
| WO-2006010637-A2 | PYRIDINYLAMINES | GPC BIOTECH AG (DE) | 2006-02-02 | — | — | WO | claimed |