Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8448289 | 0.97 | CASP1 (0.42) | CASP1NPC1RAB9APTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL8448284 | 0.97 | CASP1 (0.42) | CASP1NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL3783187 | 0.84 | AAK1 (0.48) | NPC1RAB9AALDH1A1CYP3A4MEN1 | |
| SCHEMBL11528651 | 0.82 | AAK1 (0.50) | NPC1RAB9AALDH1A1G6PDIDE | |
| SCHEMBL8920417 | 0.82 | CASP1 (0.48) | CASP1NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL9781542 | 0.82 | NPC1 (0.63) | NPC1RAB9AALDH1A1CYP3A4MEN1 | |
| SCHEMBL17498342 | 0.81 | ITGB2 (0.43) | CASP1NPC1RAB9AALDH1A1G6PD | |
| SCHEMBL30678438 | 0.80 | ALDH1A1 (0.54) | CASP1NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL9180206 | 0.80 | NPC1 (0.41) | NPC1RAB9AALDH1A1G6PDIDE | |
| SCHEMBL8491702 | 0.80 | ALDH1A1 (0.54) | CASP1NPC1RAB9APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335900-B1 | ALKYLTHIO- AND ARYL(HETEROYL)THIO-SUBSTITUTED P-PHENYLENEDIAMINES, THEIR MANUFACTURE AND THEIR USE IN RUBBER | FLEXSYS AMERICA LP (US) | 2007-04-18 | — | — | EP | claimed |
| EP-0656202-B1 | Dyeing composition containing sulphurous p-phenylene-diamines, sulphurous p-phenylenediamines and method of preparation | OREAL (FR) | 1999-05-06 | — | — | EP | claimed |
| US-5542952-A | DEVELOPERS THAT FORM STABLE OXIDATION HAIR DYES | L'OREAL (FR) | 1996-08-06 | — | — | US | claimed |
| EP-0656202-A1 | Dyeing composition containing sulphurous p-phenylene-diamines, novel sulphurous p-phenylenediamines and method of preparation | L'OREAL (FR) | 1995-06-07 | — | — | EP | claimed |
| CN-114502672-A | Coating composition | PRC-迪索托国际公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2020059048-A1 | SET COMPRISING MAIN AGENT AND CURING AGENT, WATER-RESISTANT MATERIAL, AND METHOD OF CONSTRUCTING SAME | 保土谷化学工業株式会社 | 2020-03-26 | — | — | WO | disclosed |
| EP-1335900-B1 | ALKYLTHIO- AND ARYL(HETEROYL)THIO-SUBSTITUTED P-PHENYLENEDIAMINES, THEIR MANUFACTURE AND THEIR USE IN RUBBER | FLEXSYS AMERICA LP (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-0656202-B1 | Dyeing composition containing sulphurous p-phenylene-diamines, sulphurous p-phenylenediamines and method of preparation | OREAL (FR) | 1999-05-06 | — | — | EP | disclosed |
| US-5542952-A | DEVELOPERS THAT FORM STABLE OXIDATION HAIR DYES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |
| EP-0656202-A1 | Dyeing composition containing sulphurous p-phenylene-diamines, novel sulphurous p-phenylenediamines and method of preparation | L'OREAL (FR) | 1995-06-07 | — | — | EP | disclosed |
| US-4239708-A | P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| EP-0001604-B1 | AROMATIC DIISOCYANATES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES | BAYER AG (DE) | 1980-07-23 | — | — | EP | disclosed |
| EP-0001604-A2 | Aromatic diisocyanates, process for their preparation and their use in the preparation of polyurethanes | BAYER AG (DE) | 1979-05-02 | — | — | EP | disclosed |
| US-4137310-A | LARVICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |