Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166130 | 1.00 | MEN1 (0.40) | MEN1KMT2ACYP1A1CYP1B1GABRA1 | |
| SCHEMBL27945269 | 0.81 | GABRA1 (0.41) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL9869836 | 0.81 | PTGS1 (0.39) | KDM4EALOX5PTGS1PTGS2 | |
| SCHEMBL9651833 | 0.81 | PTGS1 (0.39) | KDM4EALOX5PTGS1PTGS2 | |
| SCHEMBL6546420 | 0.80 | AMY1A (0.47) | MEN1KMT2ACYP1A1CYP1B1AMY1A | |
| SCHEMBL11323718 | 0.80 | AMY1A (0.47) | MEN1KMT2ACYP1A1CYP1B1AMY1A | |
| SCHEMBL15362107 | 0.80 | CYP1A1 (0.42) | MEN1KMT2ACYP1A1CYP1B1GABRA1 | |
| SCHEMBL15362106 | 0.80 | CYP1A1 (0.42) | MEN1KMT2ACYP1A1CYP1B1GABRA1 | |
| SCHEMBL16420007 | 0.78 | AR (0.38) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL28645929 | 0.78 | CYP2A6 (0.37) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248971-B | Copolymer and optical film using the same | 东曹株式会社 | 2021-11-02 | — | — | CN | disclosed |
| EP-0787122-B9 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMA INC (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-0787122-B1 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMA INC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1553078-A1 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2005-07-13 | — | — | EP | disclosed |
| EP-1275635-A1 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2003-01-15 | — | — | EP | disclosed |
| EP-1203761-A2 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2002-05-08 | — | — | EP | disclosed |
| US-6211244-B1 | AROMATIC AMINES FOR COMPLEXING CALCIUM | NPS PHARMACEUTICALS, INC. | 2001-04-03 | — | — | US | disclosed |
| WO-1996012697-A9 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMA INC (US) | 2000-08-24 | — | — | WO | disclosed |
| EP-0787122-A2 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996012697-A2 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1996-05-02 | — | — | WO | disclosed |