Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651833 | 1.00 | PTGS1 (0.39) | PTGS1PTGS2NFE2L2HTR2AHTR2C | |
| SCHEMBL5166135 | 0.81 | MEN1 (0.40) | PTGS1PTGS2KDM4EALOX5 | |
| SCHEMBL5166130 | 0.81 | MEN1 (0.40) | PTGS1PTGS2KDM4EALOX5 | |
| SCHEMBL11350303 | 0.78 | ALDH1A1 (0.38) | NFE2L2KDM4EENPP2 | |
| SCHEMBL19926448 | 0.78 | NFE2L2 (0.35) | NFE2L2KDM4EENPP2 | |
| SCHEMBL7480448 | 0.78 | MAOA (0.42) | NFE2L2HTR2AHTR2CKCNH2 | |
| SCHEMBL7480445 | 0.78 | MAOA (0.42) | NFE2L2HTR2AHTR2CKCNH2 | |
| SCHEMBL19926446 | 0.78 | NFE2L2 (0.35) | NFE2L2KDM4EENPP2 | |
| SCHEMBL27945269 | 0.78 | GABRA1 (0.41) | PTGS1PTGS2KDM4EALOX5 | |
| SCHEMBL13678718 | 0.76 | PTGS1 (0.43) | PTGS1PTGS2NFE2L2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015757-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4960789-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |