Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3087862 | 0.99 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5165555 | 0.93 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4ESMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL3079341 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5168369 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KMT2AKDM4EMEN1GRIN2B | |
| Hydrochloric Acid SCHEMBL3086710 | 0.89 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EMEN1GRIN2B | |
| SCHEMBL3081018 | 0.89 | ALDH1A1 (0.60) | ALDH1A1KMT2AKDM4EPOLBOPRD1 | |
| SCHEMBL5166883 | 0.88 | MCHR1 (0.55) | ALDH1A1KMT2AKDM4EMEN1OPRD1 | |
| Hydrochloric Acid SCHEMBL11194779 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KMT2AKDM4EPOLBOPRD1 | |
| SCHEMBL5168656 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4ESMN1; SMN2OPRD1 | |
| Hydrochloric Acid SCHEMBL3091514 | 0.87 | MCHR1 (0.54) | ALDH1A1KMT2AKDM4EMEN1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771417-A1 | SUBSTITUTED 3-PHENYLPIPERIDINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010577-A1 | SUBSTITUTED 3-PHENYLPIPERIDINE DERIVATIVES | Grünenthal GmbH (DE) | 2006-02-02 | — | — | WO | claimed |
| EP-1771417-A1 | SUBSTITUTED 3-PHENYLPIPERIDINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010577-A1 | SUBSTITUTED 3-PHENYLPIPERIDINE DERIVATIVES | Grünenthal GmbH (DE) | 2006-02-02 | — | — | WO | disclosed |