Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408871 | 0.81 | SLC6A2 (0.40) | MAPTPTGS2SMN1; SMN2KDM4EHPGD | |
| SCHEMBL515463 | 0.81 | MAPT (0.40) | MAPTPTGS2SMN1; SMN2KDM4EHPGD | |
| SCHEMBL10347560 | 0.80 | MAPT (0.56) | MAPTMAOBCYP3A4CYP2A6KDM4E | |
| SCHEMBL30663731 | 0.80 | MAPT (0.56) | MAPTMAOBCYP3A4CYP2A6KDM4E | |
| Hydrochloric Acid SCHEMBL21694039 | 0.78 | MAPT (0.55) | MAPTMAOBCYP3A4CYP2A6KDM4E | |
| SCHEMBL11847000 | 0.76 | ALDH1A1 (0.52) | MAPTKDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22140245 | 0.76 | MAOB (0.34) | MAPTMAOBHPGDMAOAPOLB | |
| SCHEMBL11855726 | 0.75 | MAPT (0.43) | MAPTSMN1; SMN2KDM4EHPGDSLC6A2 | |
| SCHEMBL6811036 | 0.75 | CA12 (0.54) | MAPTMAOBSMN1; SMN2MAOATDP1 | |
| SCHEMBL11848917 | 0.75 | SLC6A2 (0.40) | MAPTPTGS2SMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300405-B1 | AMINO ALCOHOL DERIVATIVES | SANKYO CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-6964976-B2 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2005-11-15 | — | — | US | disclosed |
| US-20040132784-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132784-A1 | Amino alcohol derivatives | CD4, ADH1C, ADH1A | MAPT 4611/4885MAOB 1891/4885PTGS2 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.