SCHEMBL5166313

SCHEMBL5166313

CCCCOC(=O)C(C)N1C(=O)C=CC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.42
TSHR P16473 3/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2C19 P33261 3/20 0.42
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CYP2D6 P10635 1/20 0.42
MAPK1 P28482 1/20 0.42
NR1H2 P55055 1/20 0.42
RNASEL Q05823 1/20 0.42
ALDH1A1 P00352 5/20 0.42
NPSR1 Q6W5P4 3/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
PDE4D Q08499 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
HPGD P15428 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5164105 0.95 TSHR (0.42) ESR1TSHRLMNAMAPK1ALDH1A1
SCHEMBL15023990 0.94 ESR1 (0.44) ESR1TSHRLMNAMAPK1ALDH1A1
SCHEMBL15024120 0.94 ESR1 (0.44) ESR1TSHRLMNAMAPK1ALDH1A1
SCHEMBL15023953 0.94 ESR1 (0.44) ESR1TSHRLMNAMAPK1ALDH1A1
SCHEMBL14868134 0.91 ALDH1A1 (0.38) ESR1TSHRCYP1A2CYP2C19LMNA
SCHEMBL14868162 0.91 RARB (0.40) ESR1TSHRCYP1A2CYP2C19LMNA
SCHEMBL15394143 0.91 RARB (0.40) ESR1TSHRCYP1A2CYP2C19LMNA
SCHEMBL14868142 0.90 ALDH1A1 (0.37) ESR1TSHRCYP1A2CYP2C19LMNA
SCHEMBL5160610 0.90 LMNA (0.42) ESR1TSHRCYP1A2CYP2C19LMNA
SCHEMBL14868135 0.90 ALDH1A1 (0.37) ESR1TSHRCYP1A2CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669342-B1 ACTIVE-ENERGY-RAY-CURABLE INKJET INK COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE INKJET INK, AND INKJET RECORDING METHOD KONICA MINOLTA INC (JP) 2020-03-18 EP disclosed
US-9416289-B2 Active-energy-ray-curable inkjet ink composition, active-energy-ray-curable inkjet ink, and inkjet recording method Konica Minolta, Inc. (JP) 2016-08-16 US disclosed
US-9416289-B2 Active-energy-ray-curable inkjet ink composition, active-energy-ray-curable inkjet ink, and inkjet recording method Konica Minolta, Inc. (JP) 2016-08-16 US disclosed
US-9175180-B2 Inkjet ink and inkjet image formation method using same Konica Minolta, Inc. (JP) 2015-11-03 US disclosed
US-9175180-B2 Inkjet ink and inkjet image formation method using same Konica Minolta, Inc. (JP) 2015-11-03 US disclosed
US-20140130709-A1 PHOTOCURABLE INK JET INK KONICA MINOLTA , INC. (JP) 2014-05-15 US disclosed
US-20140130709-A1 PHOTOCURABLE INK JET INK KONICA MINOLTA , INC. (JP) 2014-05-15 US disclosed
EP-2722372-A1 PHOTOCURABLE INK JET INK Konica Minolta, Inc. (JP) 2014-04-23 EP disclosed
US-20130307913-A1 ACTIVE-ENERGY-RAY-CURABLE INKJET INK COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE INKJET INK, AND INKJET RECORDING METHOD Konica Minolta, Inc. (JP) 2013-11-21 US disclosed
EP-2584011-A1 INKJET INK AND INKJET IMAGE FORMATION METHOD USING SAME Konica Minolta Holdings, Inc. (JP) 2013-04-24 EP disclosed
US-20130095236-A1 INKJET INK AND INKJET IMAGE FORMATION METHOD USING SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-18 US disclosed
US-20130095236-A1 INKJET INK AND INKJET IMAGE FORMATION METHOD USING SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-18 US disclosed
EP-1582548-B1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK & CHEMICALS (JP) 2007-03-28 EP disclosed
US-7141642-B2 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-11-28 US disclosed
US-20060047140-A1 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-03-02 US disclosed
EP-1582548-A1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047140-A1 Process for producing polymerizable polybranched polyester ACSL4, ACSL1, HACL2 ESR1 895/4885TSHR 3899/4885CYP1A2 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.