Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | ATF4 | P18848 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024143 | 1.00 | VCP (0.46) | VCPKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL5025581 | 0.89 | LSS (0.41) | VCPKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL7176064 | 0.77 | HPGD (0.47) | KMT2ATDP1NPC1RAB9AATF4 | |
| SCHEMBL9680408 | 0.75 | PARP15 (0.54) | S1PR5MAPTATF4 | |
| SCHEMBL6018945 | 0.73 | ALDH1A1 (0.38) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL17658712 | 0.73 | NPC1 (0.56) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL5024153 | 0.73 | LSS (0.54) | VCPKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL5024147 | 0.73 | LSS (0.54) | VCPKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL7361058 | 0.72 | ALDH1A1 (0.58) | VCPNPC1RAB9AALDH1A1CYP2C9 | |
| SCHEMBL5025584 | 0.71 | LSS (0.70) | VCPKMT2AMEN1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768658-A1 | HYDROXYALKYLAMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006125451-A1 | HYDROXYALKYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-30 | — | — | WO | disclosed |