Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 11/20 | 0.47 |
| ▸ | THRB | P10828 | 11/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51701 | 0.88 | TRPA1 (0.59) | TRPA1HSP90AA1HSP90AB1GABRA1GABRB2 | |
| SCHEMBL4392926 | 0.85 | THRA (0.55) | TRPA1HSP90AA1HSP90AB1THRATHRB | |
| SCHEMBL12949905 | 0.85 | THRA (0.51) | TRPA1HSP90AA1HSP90AB1THRATHRB | |
| SCHEMBL1860686 | 0.84 | CNR1 (0.60) | HSP90AA1HSP90AB1THRATHRBGABRA1 | |
| SCHEMBL9461082 | 0.84 | TRPA1 (0.55) | TRPA1HSP90AA1HSP90AB1THRATHRB | |
| SCHEMBL5382094 | 0.83 | THRA (0.47) | TRPA1HSP90AA1HSP90AB1THRATHRB | |
| SCHEMBL5520591 | 0.83 | TRPA1 (0.59) | TRPA1HSP90AA1HSP90AB1GABRA1GABRB2 | |
| SCHEMBL4610099 | 0.83 | TRPA1 (0.59) | TRPA1HSP90AA1HSP90AB1GABRA1GABRB2 | |
| SCHEMBL10821782 | 0.82 | THRA (0.46) | TRPA1HSP90AA1HSP90AB1THRATHRB | |
| SCHEMBL10947856 | 0.82 | THRA (0.47) | TRPA1HSP90AA1HSP90AB1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596873-B | Novel trisphenol compound | HONSHU CHEMICAL IND | 2014-11-12 | — | — | CN | claimed |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2017-12-21 | — | — | US | disclosed |
| CN-102163013-B | Electrophotographic photoreceptor and image forming apparatus using the same | MITSUBISHI CHEM CORP | 2015-02-18 | — | — | CN | disclosed |
| CN-102596873-B | Novel trisphenol compound | HONSHU CHEMICAL IND | 2014-11-12 | — | — | CN | disclosed |
| CN-102169298-B | Image forming apparatus with a plurality of image forming units | MITSUBISHI CHEM CORP | 2014-01-08 | — | — | CN | disclosed |
| CN-102156394-B | Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same | MITSUBISHI CHEM CORP | 2013-09-25 | — | — | CN | disclosed |
| CN-102221793-B | Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same | MITSUBISHI CHEM CORP | 2013-07-31 | — | — | CN | disclosed |
| CN-102169297-B | Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same | MITSUBISHI CHEM CORP | 2013-07-31 | — | — | CN | disclosed |
| CN-101817713-B | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-102596873-A | Novel trisphenol compound | HONSHU CHEMICAL IND | 2012-07-18 | — | — | CN | disclosed |
| EP-0595979-A1 | POLYMERIZATION PROCESS AND PRODUCTS. | SHELL OIL CO (US) | 1994-05-11 | — | — | EP | disclosed |
| EP-0593653-A1 | POLYMERIZATION PROCESS AND PRODUCTS. | SHELL OIL CO (US) | 1994-04-27 | — | — | EP | disclosed |
| EP-0588800-A1 | POLYMERIZATION PROCESS AND PRODUCTS. | SHELL OIL CO (US) | 1994-03-30 | — | — | EP | disclosed |
| WO-1993002121-A1 | POLYMERIZATION PROCESS AND PRODUCTS | SHELL OIL COMPANY (US) | 1993-02-04 | — | — | WO | disclosed |
| WO-1993001223-A1 | POLYMERIZATION PROCESS AND PRODUCTS | SHELL OIL COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| CN-1067661-A | Polymerisation process | SHELL OIL CO (US) | 1993-01-06 | — | — | CN | disclosed |
| WO-1992022597-A1 | POLYMERIZATION PROCESS AND PRODUCTS | SHELL OIL COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |
| US-5143992-A | Methathesis polymerizable adducts of a divinylcyclohydrocarbon and cyclopentadiene | SHELL OIL COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| US-5095082-A | Polymerization process employing mixture of Diels-Alder adducts of 4-vinylcyclohexene and cyclopentadiene | SHELL OIL COMPANY (US) | 1992-03-10 | — | — | US | disclosed |
| US-4077962-A | WATER INSOLUBLE, GREEN-YELLOW, SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | ESR1, ESRRA, ESR2 | TRPA1 2845/4885HSP90AA1 4318/4885HSP90AB1 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.