Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51468 | 0.88 | TRPA1 (0.59) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL31545856 | 0.85 | SLC6A2 (0.57) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL21034794 | 0.85 | SLC6A2 (0.57) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL16736618 | 0.84 | TSHR (0.57) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL5168817 | 0.84 | CNR1 (0.55) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL5166554 | 0.83 | TRPA1 (0.59) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL28662759 | 0.82 | TRPA1 (0.57) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL5167759 | 0.82 | GABRA1 (0.58) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL5164400 | 0.81 | NPC1 (0.56) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL25497961 | 0.81 | PTGS2 (0.52) | TRPA1LMNACHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670423-B1 | DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-10-08 | — | — | EP | claimed |
| EP-4103576-A1 | 3'-KETOGLYCOSIDE COMPOUND FOR THE SLOW RELEASE OF A VOLATILE ALCOHOL | Glycoscience, S.L. (ES) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021160670-A1 | 3'-KETOGLYCOSIDE COMPOUND FOR THE SLOW RELEASE OF A VOLATILE ALCOHOL | GLYCOSCIENCE, S.L. (ES) | 2021-08-19 | — | — | WO | disclosed |
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170174600-A1 | 2,5-DIALKYL-4-H/HALO/ETHER-PHENOL COMPOUNDS | TANSNA THERAPEUTICS, INC. | 2017-06-22 | — | — | US | disclosed |
| US-20170174600-A1 | 2,5-DIALKYL-4-H/HALO/ETHER-PHENOL COMPOUNDS | TANSNA THERAPEUTICS, INC. | 2017-06-22 | — | — | US | disclosed |
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-08-28 | — | — | US | disclosed |
| CN-101817713-B | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-101817713-A | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2010-09-01 | — | — | CN | disclosed |
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1633691-B1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| CN-1802339-A | Method for producing 2,2'-dihydroxy-biphenyls | BASF AG (DE) | 2006-07-12 | — | — | CN | disclosed |
| EP-1633691-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004108642-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004069779-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-19 | — | — | WO | disclosed |
| US-4085132-A | Process for the production of hydroxyalkylphenyl derivatives | CIBA-GEIGY CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | HAO2, DAO, DDO | TRPA1 3071/4885LMNA 591/4885CHRM1 2300/4885 |
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | WEE1, WEE2, NOTUM | TRPA1 1385/4885LMNA 3378/4885CHRM1 4870/4885 |
| US-20170174600-A1 | 2,5-DIALKYL-4-H/HALO/ETHER-PHENOL COMPOUNDS | COMT, DDT, TYR | TRPA1 1054/4885LMNA 2070/4885CHRM1 453/4885 |
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | MMP8, GUSB, MMP9 | TRPA1 656/4885LMNA 975/4885CHRM1 4818/4885 |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | TRPA1 656/4885LMNA 975/4885CHRM1 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.