Acetic Acid

Acetic Acid

SCHEMBL5166708

CC(=O)O.COCCOCCOCCOC

nearest known ligand 0.42

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2B known ✓ P18089 1/20 0.34
SCN5A known ✓ Q14524 1/20 0.34
ALDH1A1 P00352 6/20 0.42
FFAR3 O14843 1/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
CA2 P00918 1/20 0.40
TSHR P16473 5/20 0.39
HSD17B10 Q99714 2/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.34
ABCB11 O95342 1/20 0.34
CYP3A4 P08684 1/20 0.34
OPRD1 P41143 1/20 0.34
EPHX2 P34913 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 2/20 0.33
HIF1A Q16665 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL775971 1.00 ALDH1A1 (0.42) ALDH1A1FFAR3LCKFYNCA2
Acetic Acid SCHEMBL8395404 0.97 ALDH1A1 (0.41) ALDH1A1FFAR3LCKFYNCA2
Bicarbonate SCHEMBL9083427 0.91 ALDH1A1 (0.44) ALDH1A1CA2TSHRHSD17B10BLM
Acetone SCHEMBL11555965 0.91 CA2 (0.41) ALDH1A1CA2TSHRHSD17B10SMN1; SMN2
Bicarbonate SCHEMBL27364872 0.91 ALDH1A1 (0.44) ALDH1A1CA2TSHRHSD17B10BLM
Acetic Acid SCHEMBL7261899 0.91 FFAR3 (0.50) ALDH1A1FFAR3LCKFYNCA2
Acetic Acid SCHEMBL774951 0.91 FFAR3 (0.50) ALDH1A1FFAR3LCKFYNCA2
Acetic Acid SCHEMBL356157 0.90 ALDH1A1 (0.38) ALDH1A1FFAR3LCKFYNCA2
Acetic Acid SCHEMBL2515140 0.90 MEN1 (0.52) ALDH1A1FFAR3LCKFYNCA2
Acetic Acid SCHEMBL4453838 0.90 ALDH1A1 (0.54) ALDH1A1FFAR3LCKFYNCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2881442-B1 POLYISOCYANATE COMPOSITION, SOLAR CELL MEMBER COVERING MATERIAL, SOLAR CELL MEMBER WITH COVERING LAYER, MICROCAPSULE, AND INK BINDER MITSUI CHEMICALS INC (JP) 2018-09-05 EP disclosed
US-9822212-B2 Polyisocyanate composition, solar cell member covering material, solar cell member with cover layer, microcapsule, and binder for ink MITSUI CHEMICALS, INC. (JP) 2017-11-21 US disclosed
US-20150183922-A1 POLYISOCYANATE COMPOSITION, SOLAR CELL MEMBER COVERING MATERIAL, SOLAR CELL MEMBER WITH COVER LAYER, MICROCAPSULE, AND BINDER FOR INK MITSUI CHEMICALS, INC. (JP) 2015-07-02 US disclosed
EP-2881442-A1 POLYISOCYANATE COMPOSITION, SOLAR CELL MEMBER COVERING MATERIAL, SOLAR CELL MEMBER WITH COVERING LAYER, MICROCAPSULE, AND INK BINDER Mitsui Chemicals, Inc. (JP) 2015-06-10 EP disclosed
WO-2007068028-A1 PHOTOLUMINESCENT TEXTILE MATERIALS THE SPECIALTY GROUP (AU) 2007-06-21 WO disclosed
EP-1476509-B1 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2007-04-11 EP disclosed
US-7192682-B2 Unsaturated monomers, polymers, chemically-amplified resist composition, and process of pattern formation NEC CORPORATION (JP) 2007-03-20 US disclosed
US-20040265732-A1 Unsaturated monomers, polymers, chemically amplified resist composition, and process of pattern formation NEC CORPORATION (JP) 2004-12-30 US disclosed
EP-1476509-A2 SELF-POLISHING ANTIFOULING PAINT Jotun AS (NO) 2004-11-17 EP disclosed
WO-2003070832-A2 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2003-08-28 WO disclosed
US-4876302-A POLYUREA-URETHANES BAYER AKTIENGESELLSCHAFT (DE) 1989-10-24 US disclosed