Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.34 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5166708 | 1.00 | ALDH1A1 (0.42) | ALDH1A1FFAR3LCKFYNCA2 | |
| Acetic Acid SCHEMBL8395404 | 0.97 | ALDH1A1 (0.41) | ALDH1A1FFAR3LCKFYNCA2 | |
| Bicarbonate SCHEMBL9083427 | 0.91 | ALDH1A1 (0.44) | ALDH1A1CA2TSHRHSD17B10BLM | |
| Acetone SCHEMBL11555965 | 0.91 | CA2 (0.41) | ALDH1A1CA2TSHRHSD17B10SMN1; SMN2 | |
| Bicarbonate SCHEMBL27364872 | 0.91 | ALDH1A1 (0.44) | ALDH1A1CA2TSHRHSD17B10BLM | |
| Acetic Acid SCHEMBL7261899 | 0.91 | FFAR3 (0.50) | ALDH1A1FFAR3LCKFYNCA2 | |
| Acetic Acid SCHEMBL774951 | 0.91 | FFAR3 (0.50) | ALDH1A1FFAR3LCKFYNCA2 | |
| Acetic Acid SCHEMBL356157 | 0.90 | ALDH1A1 (0.38) | ALDH1A1FFAR3LCKFYNCA2 | |
| Acetic Acid SCHEMBL2515140 | 0.90 | MEN1 (0.52) | ALDH1A1FFAR3LCKFYNCA2 | |
| Acetic Acid SCHEMBL4453838 | 0.90 | ALDH1A1 (0.54) | ALDH1A1FFAR3LCKFYNCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110144142-A | A kind of nano-oxide ink, preparation method and electroluminescent device | 广东普加福光电科技有限公司 | 2019-08-20 | — | — | CN | claimed |
| CN-106085070-B | A kind of low-surface-energy micro nano-coatings material and preparation method thereof | 复旦大学 | 2019-07-05 | — | — | CN | claimed |
| CN-106189631-B | A kind of aircraft wing based on micro nano-coatings turns to twist related method thereof | 复旦大学 | 2019-07-05 | — | — | CN | claimed |
| CN-109599508-A | Electroluminescent device and preparation method thereof | 嘉兴纳鼎光电科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-109370312-A | A kind of quantum dot ink and its application | 苏州佳生物科技有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-109135532-A | The double-component aqueous PU plastic paint and its preparation process of scintilla water dispersion | 深圳市莱莉雅环保科技有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-104668575-B | A kind of nano-silver powder being dispersed in Weak solvent and its application for preparing electrically conductive ink | 中国科学院化学研究所 | 2019-01-04 | — | — | CN | claimed |
| CN-108182985-A | The photosensitive silver paste of organic carrier and the application organic carrier | 富泰华工业（深圳）有限公司 | 2018-06-19 | — | — | CN | claimed |
| CN-108017747-A | A kind of alkali soluble resins polymer, its preparation method and photosensitive polymer combination | 固安鼎材科技有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-108003290-A | A kind of alkali soluble resins polymer, its preparation method and photosensitive polymer combination and their application | 固安鼎材科技有限公司 | 2018-05-08 | — | — | CN | claimed |
| CN-106085070-A | A kind of low-surface-energy micro nano-coatings material and preparation method thereof | 复旦大学 | 2016-11-09 | — | — | CN | claimed |
| CN-104231150-B | Alkali soluble resins polymer and preparation method thereof | 北京鼎材科技有限公司 | 2016-08-31 | — | — | CN | claimed |
| CN-104668575-A | Nanometer silver powder dispersible in weak solvents and application of nanometer silver powder to conductive ink preparation | CHINESE ACAD INST CHEMISTRY | 2015-06-03 | — | — | CN | claimed |
| US-8822127-B2 | Photosensitive resin composition for black matrix | LG CHEM, LTD. (KR) | 2014-09-02 | — | — | US | claimed |
| US-20110151379-A1 | BLACK MATRIX COMPOSITION WITH HIGH LIGHT-SHIELDING AND IMPROVED ADHESION PROPERTIES | LG CHEM, LTD. (KR) | 2011-06-23 | — | — | US | claimed |
| US-20110101268-A1 | PHOTOSENSITIVE RESIN COMPOSITION FOR BLACK MATRIX | LG CHEM, LTD. (KR) | 2011-05-05 | — | — | US | claimed |
| CN-100538517-C | Negative resist composition for organic insulating layer of high aperture LCD | ADMS TECHNOLOGY CO LTD (KR) | 2009-09-09 | — | — | CN | claimed |
| CN-1781057-A | Negative resist composition for organic insulating layer of high aperture LCD | ADMS TECHNOLOGY CO LTD (KR) | 2006-05-31 | — | — | CN | claimed |
| US-5118392-A | Introducing extractive agent to increase relative volatility | Berg, Lloyd (US) | 1992-06-02 | — | — | US | claimed |
| US-4545818-A | WETTING AGENT, COLORING AGENT, XANTHAN GUM, AND PERMEABLE SOLVENT | UNITED KINGDOM ATOMIC ENERGY AUTHORITY (GB) | 1985-10-08 | — | — | US | claimed |