Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL27914030 | 0.86 | TSHR (0.38) | TSHRHPGDHCAR2KEAP1NFE2L2 | |
| Acrylic Acid SCHEMBL6686326 | 0.84 | LMNA (0.48) | TSHRHPGDHSD17B10ALOX15LMNA | |
| Acrylic Acid SCHEMBL2152793 | 0.84 | LMNA (0.48) | TSHRHPGDHSD17B10ALOX15LMNA | |
| Acrylic Acid Ethyl Ester SCHEMBL11847163 | 0.84 | TSHR (0.43) | TSHRHPGDHSD17B10HCAR2LMNA | |
| Acrylic Acid Methyl Ester SCHEMBL27193050 | 0.83 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL6920652 | 0.81 | TSHR (0.41) | TSHRHPGDHSD17B10ALDH1A1TP53 | |
| SCHEMBL3429278 | 0.80 | ALDH1A1 (0.43) | TSHRHSD17B10ALOX15LMNAALDH1A1 | |
| Acrylic Acid Methyl Ester SCHEMBL1245380 | 0.80 | HCAR2 (0.39) | TSHRHPGDHSD17B10ALOX15HCAR2 | |
| Butadiene SCHEMBL8409931 | 0.80 | GRIK1 (0.35) | TSHRHSD17B10ALOX15LMNAALDH1A1 | |
| Acrylic Acid Methyl Ester SCHEMBL22749612 | 0.80 | LMNA (0.48) | TSHRHPGDHSD17B10ALOX15HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007062-A2 | CARTILAGE REPAIR IMPLANT | DEPUY INTERNATIONAL LIMITED (GB) | 2007-01-18 | — | — | WO | disclosed |