SCHEMBL6920652

SCHEMBL6920652

C=CCOC(=O)C=C.CCC=C(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.41
HPGD P15428 1/20 0.41
MAPT P10636 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 4/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
CYP3A4 P08684 3/20 0.36
HSD17B10 Q99714 1/20 0.36
THRB P10828 2/20 0.35
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
APP P05067 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Ethyl Ester SCHEMBL11847163 0.86 TSHR (0.43) TSHRHPGDMAPTALDH1A1TP53
SCHEMBL28056594 0.84 TSHR (0.41) TSHRHPGDMAPTCACNA1BAPBA1
SCHEMBL8425135 0.84 TSHR (0.44) TSHRHPGDMAPTCACNA1BAPBA1
SCHEMBL28212051 0.82 TSHR (0.52) TSHRHPGDMAPTCACNA1BAPBA1
Acetic Acid SCHEMBL460344 0.82 TSHR (0.48) TSHRHPGDMAPTCACNA1BAPBA1
Acrylic Acid Methyl Ester SCHEMBL5166727 0.81 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL8516311 0.81 TSHR (0.41) TSHRHPGDMAPTCACNA1BAPBA1
SCHEMBL29842279 0.81 TSHR (0.69) TSHRHPGDMAPTALDH1A1TP53
Methacrylic Acid SCHEMBL316282 0.80 TSHR (0.44) TSHRHPGDMAPTCACNA1BAPBA1
Acrylic Acid SCHEMBL170500 0.80 TSHR (0.48) TSHRHPGDMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10619071-B2 Coating compositions for coating fibre cement board BASF SE (DE) 2020-04-14 US disclosed
EP-3365309-B1 COATING COMPOSITIONS FOR COATING FIBRE CEMENT BOARD BASF SE (DE) 2019-09-25 EP disclosed
US-20180305574-A1 COATING COMPOSITIONS FOR COATING FIBRE CEMENT BOARD BASF SE (DE) 2018-10-25 US disclosed
EP-3365309-A1 COATING COMPOSITIONS FOR COATING FIBRE CEMENT BOARD BASF SE (DE) 2018-08-29 EP disclosed
WO-2017067957-A1 COATING COMPOSITIONS FOR COATING FIBRE CEMENT BOARD BASF SE (DE) 2017-04-27 WO disclosed
CN-101262848-B Antifungal composition NOVARTIS AG 2011-05-11 CN disclosed
CN-101262848-A Antifungal composition NOVARTIS AG (CH) 2008-09-10 CN disclosed
US-6740696-B1 RETAINING IMPACT STRENGTH UPON EXPOSURE TO HEAT AND HUMIDITY GENERAL ELECTRIC COMPANY 2004-05-25 US disclosed
EP-0771851-B1 Flame retardant polycarbonate blends comprising graft copolymers GEN ELECTRIC (US) 2003-05-07 EP disclosed
EP-0771851-A2 Flame retardant polycarbonate blends comprising graft copolymers GENERAL ELECTRIC COMPANY (US) 1997-05-07 EP disclosed
EP-0714949-A2 Processes, thermoplastic compositions and emulsion graft copolymer utilizing a polyacid GENERAL ELECTRIC COMPANY (US) 1996-06-05 EP disclosed
EP-0714943-A2 Impact modifier vinyl chloride resin composition, and graft copolymer compositions GENERAL ELECTRIC COMPANY (US) 1996-06-05 EP disclosed