Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | PARP1 | P09874 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | GPR3 | P46089 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TNKS | O95271 | 2/20 | 0.59 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | IDE | P14735 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229455 | 0.82 | KDM4E (0.69) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL28784055 | 0.82 | DAO (0.62) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL14339328 | 0.82 | DAO (0.58) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL31175987 | 0.82 | KDM4E (0.53) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL476707 | 0.82 | KDM4E (0.53) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL29096075 | 0.82 | KDM4E (0.53) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL1239816 | 0.79 | MAPT (0.65) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL14339329 | 0.79 | KDM4E (0.50) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL27782857 | 0.79 | MAPT (0.60) | KDM4EPARP1ALDH1A1LMNAGPR3 | |
| SCHEMBL13997679 | 0.77 | KDM4E (0.72) | KDM4EPARP1ALDH1A1LMNAGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110495464-B | Herbicidal composition containing quinclorac and application thereof | 安徽尚禾沃达生物科技有限公司 | 2021-06-22 | — | — | CN | claimed |
| CN-110495464-B | Herbicidal composition containing quinclorac and application thereof | 安徽尚禾沃达生物科技有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-109964943-B | Herbicidal compositions comprising pyrimidinyloximes and their use | 江苏清原农冠杂草防治有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-111149800-A | Fenoxaprop-p-ethyl resistant composition for rice | 江西中迅农化有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-110870481-A | Herbicidal composition containing heterocyclic amide compound and application thereof | 青岛清原化合物有限公司 | 2020-03-10 | — | — | CN | disclosed |
| WO-2020015105-A1 | BINARY HERBICIDAL COMPOSITION CONTAINING HPPD-INHIBITOR HERBICIDE AND USE THEREOF | 青岛清原化合物有限公司 | 2020-01-23 | — | — | WO | disclosed |
| CN-110679596-A | Weeding composition containing quinclorac and propyrisulfuron | 广东中迅农科股份有限公司 | 2020-01-14 | — | — | CN | disclosed |
| US-7312220-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312221-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-12-25 | — | — | US | disclosed |
| US-20070270395-A1 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | AVANIR PHARMACEUTICALS (US) | 2007-11-22 | — | — | US | disclosed |
| US-7235546-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-06-26 | — | — | US | disclosed |
| US-20070054923-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2007-03-08 | — | — | US | disclosed |
| US-20070054922-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2007-03-08 | — | — | US | disclosed |
| US-20070054898-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2007-03-08 | — | — | US | disclosed |
| US-20070054920-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2007-03-08 | — | — | US | disclosed |
| US-7173036-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-02-06 | — | — | US | disclosed |
| EP-1594501-A4 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | AVANIR PHARMACEUTICALS (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1594501-A2 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | Avanir Pharmaceuticals (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20040204586-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS, INC. | 2004-10-14 | — | — | US | disclosed |
| WO-2004074218-A2 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | AVANIR PHARMACEUTICALS (US) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270395-A1 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | MIF, MSR1, MMP12 | KDM4E 2968/4885PARP1 4301/4885ALDH1A1 1799/4885 |
| US-20070054898-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | MIF, MSR1, MMP12 | KDM4E 2968/4885PARP1 4301/4885ALDH1A1 1799/4885 |
| US-20070054920-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | MIF, MSR1, MMP12 | KDM4E 2968/4885PARP1 4301/4885ALDH1A1 1799/4885 |
| US-20040204586-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | MIF, MSR1, MMP12 | KDM4E 3206/4885PARP1 4413/4885ALDH1A1 1446/4885 |
| US-20070054923-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | MIF, MSR1, MMP12 | KDM4E 2968/4885PARP1 4301/4885ALDH1A1 1799/4885 |
| US-20070054922-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | MIF, MSR1, MMP12 | KDM4E 2968/4885PARP1 4301/4885ALDH1A1 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.