Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620052 | 0.85 | HTT (0.34) | HSD17B3HTTALOX15HSD17B10 | |
| SCHEMBL18306076 | 0.77 | PARP1 (0.32) | MEN1KMT2A | |
| SCHEMBL715561 | 0.75 | HSD17B10 (0.33) | HSD17B3ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL6204990 | 0.73 | HSD17B3 (0.33) | HSD17B3ALOX15HSD17B10 | |
| SCHEMBL5695892 | 0.71 | P2RX7 (0.34) | MEN1KMT2A | |
| SCHEMBL20916945 | 0.70 | DAO (0.47) | MEN1KMT2AHTT | |
| SCHEMBL980578 | 0.69 | MAOA (0.35) | HSD17B3ALOX15HSD17B10 | |
| SCHEMBL29816130 | 0.69 | MAOA (0.35) | HSD17B3ALOX15HSD17B10 | |
| SCHEMBL5473144 | 0.69 | MAPT (0.42) | KMT2AHSD17B3 | |
| SCHEMBL5483296 | 0.69 | HSD17B3 (0.33) | HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768973-A1 | SUBSTITUTED QUINOLONES | AiCuris GmbH & Co. KG (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008046-A1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO. KG (DE) | 2006-01-26 | — | — | WO | disclosed |