Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166843 | 0.85 | MEN1 (0.34) | HTTHSD17B3ALOX15HSD17B10 | |
| SCHEMBL980578 | 0.74 | MAOA (0.35) | HSD17B3ALOX15HSD17B10BRPF1GAA | |
| SCHEMBL29816130 | 0.74 | MAOA (0.35) | HSD17B3ALOX15HSD17B10BRPF1GAA | |
| SCHEMBL20916945 | 0.73 | DAO (0.47) | HTTGAA | |
| Hydrochloric Acid SCHEMBL3719374 | 0.72 | BLM (0.34) | HSD17B3ALOX15HSD17B10BRPF1GAA | |
| Hydrochloric Acid SCHEMBL27489771 | 0.72 | BLM (0.34) | HSD17B3ALOX15HSD17B10BRPF1GAA | |
| SCHEMBL1067728 | 0.70 | MAOA (0.50) | — | |
| SCHEMBL32670831 | 0.70 | ALDH1A1 (0.42) | ALOX15HSD17B10GAAMAPT | |
| SCHEMBL27471691 | 0.70 | MAPT (0.33) | HSD17B3ALOX15HSD17B10BRPF1GAA | |
| SCHEMBL6640943 | 0.70 | HSD17B3 (0.32) | HSD17B3ALOX15HSD17B10BRPF1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |
| EP-0172651-B1 | Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acids; substituted-5-amino-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1990-02-07 | — | — | EP | claimed |
| EP-1902030-A1 | SUBSTITUTED QUINOLONES II | AiCuris GmbH & Co. KG (DE) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007003308-A1 | SUBSTITUTED QUINOLONES II | AICURIS GMBH & CO. KG (DE) | 2007-01-11 | — | — | WO | disclosed |