SCHEMBL5166900

SCHEMBL5166900

COC(OC)c1c(F)c(F)c(C=O)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8573158 0.78
SCHEMBL5166895 0.77 CYP1A2 (0.31)
SCHEMBL22107881 0.74
SCHEMBL809345 0.72 VCP (0.33)
SCHEMBL18241122 0.70 ERN1 (0.35)
SCHEMBL5170537 0.70
SCHEMBL14031904 0.70 IGF1R (0.32)
SCHEMBL419449 0.69 VCP (0.38)
SCHEMBL1808857 0.67 VCP (0.36)
SCHEMBL28165391 0.67 ERN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1182184-B1 PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS SHOWA DENKO KK (JP) 2007-04-18 EP claimed
EP-1182184-B1 PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS SHOWA DENKO KK (JP) 2007-04-18 EP disclosed
US-6624336-B1 Acetalization of tetrafluorobenzonitriles using alcohols, in the presence of mineral acids and metal catalysts to form chemical intermediates for nontoxic insecticides SHOWA DENKO K.K. (JP) 2003-09-23 US disclosed
EP-1182184-A1 PROCESS FOR PRODUCING TETRAFLUORO BENZENEMETHANOLS Showa Denko K K (JP) 2002-02-27 EP disclosed