SCHEMBL5166895

SCHEMBL5166895

COC(C)OC.O=Cc1c(F)c(F)c(C=O)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
ERN1 O75460 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5167620 0.86 ALDH1A1 (0.37) CYP1A2MAPTCYP2C9CYP2C19ERN1
SCHEMBL5166900 0.77
SCHEMBL5170531 0.76 LMNA (0.50)
SCHEMBL809345 0.76 VCP (0.33)
SCHEMBL7563683 0.74 LMNA (0.48)
SCHEMBL18241122 0.73 ERN1 (0.35) MAPTERN1
SCHEMBL419449 0.73 VCP (0.38)
SCHEMBL5167544 0.71 ALDH1A1 (0.34) ERN1
SCHEMBL1808857 0.70 VCP (0.36)
SCHEMBL3207667 0.70 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1182184-B1 PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS SHOWA DENKO KK (JP) 2007-04-18 EP claimed
EP-1182184-B1 PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS SHOWA DENKO KK (JP) 2007-04-18 EP disclosed
US-6624336-B1 Acetalization of tetrafluorobenzonitriles using alcohols, in the presence of mineral acids and metal catalysts to form chemical intermediates for nontoxic insecticides SHOWA DENKO K.K. (JP) 2003-09-23 US disclosed
EP-1182184-A1 PROCESS FOR PRODUCING TETRAFLUORO BENZENEMETHANOLS Showa Denko K K (JP) 2002-02-27 EP disclosed