SCHEMBL5167062

SCHEMBL5167062

C1COC(CO[Si](OCC2CCCO2)(OCC2CCCO2)OCC2CCCO2)C1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
POLB P06746 2/20 0.47
ALDH1A1 P00352 3/20 0.44
NPSR1 Q6W5P4 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 1/20 0.35
USP2 O75604 1/20 0.35
MCL1 Q07820 1/20 0.35
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5167501 0.84 POLB (0.46) LMNAPOLBALDH1A1NPSR1NPC1
SCHEMBL8832657 0.84 POLB (0.46) LMNAPOLBALDH1A1NPSR1CYP1A2
SCHEMBL6476006 0.83 LMNA (0.49) LMNAPOLBALDH1A1NPSR1SMN1; SMN2
SCHEMBL16600882 0.78 LMNA (0.41) LMNAPOLBALDH1A1SMN1; SMN2NPC1
SCHEMBL812840 0.78 LMNA (0.52) LMNAPOLBALDH1A1NPSR1SMN1; SMN2
SCHEMBL1733973 0.78 LMNA (0.52) LMNAPOLBALDH1A1NPSR1SMN1; SMN2
SCHEMBL23230707 0.78 POLB (0.41) LMNAPOLBALDH1A1NPSR1CYP1A2
SCHEMBL24338139 0.78 POLB (0.41) LMNAPOLBALDH1A1NPSR1CYP1A2
SCHEMBL11050141 0.78 LMNA (0.41) LMNAPOLBALDH1A1NPSR1SMN1; SMN2
SCHEMBL18294599 0.78 POLB (0.41) LMNAPOLBALDH1A1NPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425444-B1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2007-04-25 EP claimed
US-7189794-B2 Non-pilling polyester fibres TREVIRA GMBH (DE) 2007-03-13 US claimed
US-20040143054-A1 Non-pilling polyester fibres TREVIRA GMBH (DE) 2004-07-22 US claimed
EP-1425444-A1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2004-06-09 EP claimed
WO-2003000968-A1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2003-01-03 WO claimed
EP-1425444-B1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2007-04-25 EP disclosed
EP-1425444-B1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2007-04-25 EP disclosed
US-7189794-B2 Non-pilling polyester fibres TREVIRA GMBH (DE) 2007-03-13 US disclosed
US-7189794-B2 Non-pilling polyester fibres TREVIRA GMBH (DE) 2007-03-13 US disclosed
US-7189794-B2 Non-pilling polyester fibres TREVIRA GMBH (DE) 2007-03-13 US disclosed
CN-1244728-C non-pilling polyester fibres TREVIRA GMBH (DE) 2006-03-08 CN disclosed
CN-1518613-A Non-pilling polyester fibers ά 2004-08-04 CN disclosed
US-20040143054-A1 Non-pilling polyester fibres TREVIRA GMBH (DE) 2004-07-22 US disclosed
US-20040143054-A1 Non-pilling polyester fibres TREVIRA GMBH (DE) 2004-07-22 US disclosed
EP-1425444-A1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2004-06-09 EP disclosed
EP-1425444-A1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2004-06-09 EP disclosed
WO-2003000968-A1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2003-01-03 WO disclosed
WO-2003000968-A1 NON-PILLING POLYESTER FIBRES TREVIRA GMBH (DE) 2003-01-03 WO disclosed
US-4483954-A FOR POLYMERS NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1984-11-20 US disclosed