SCHEMBL6476006

SCHEMBL6476006

O[Si](O)(O)OCC1CCCO1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
POLB P06746 1/20 0.49
ALDH1A1 P00352 2/20 0.46
NPSR1 Q6W5P4 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
USP2 O75604 1/20 0.37
MCL1 Q07820 1/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9747182 0.87 LMNA (0.40) LMNAPOLBALDH1A1NPSR1SMN1; SMN2
SCHEMBL5167062 0.83 LMNA (0.47) LMNAPOLBALDH1A1NPSR1SMN1; SMN2
SCHEMBL8832657 0.81 POLB (0.46) LMNAPOLBALDH1A1NPSR1KMT2A
SCHEMBL5167501 0.81 POLB (0.46) LMNAPOLBALDH1A1NPSR1NPC1
SCHEMBL7195828 0.76
SCHEMBL16600882 0.75 LMNA (0.41) LMNAPOLBALDH1A1SMN1; SMN2NPC1
SCHEMBL1733973 0.75 LMNA (0.52) LMNAPOLBALDH1A1NPSR1SMN1; SMN2
SCHEMBL812840 0.75 LMNA (0.52) LMNAPOLBALDH1A1NPSR1SMN1; SMN2
SCHEMBL27697712 0.75
SCHEMBL24338139 0.75 POLB (0.41) LMNAPOLBALDH1A1NPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679463-A POLYDIMETHYLSILOXANE ELASTOMER; THERMOCONDUCTIVITY; ELECTROSTATOGRAPHIC FUSING EASTMAN KODAK COMPANY (US) 1997-10-21 US claimed
CN-110945004-A Composition comprising furfuryl silicate and furfuryl alcohol 胡坦斯·阿尔伯图斯化学厂有限公司 2020-03-31 CN disclosed
US-6843559-B2 Phase change ink imaging component with MICA-type silicate layer XEROX CORPORATION (US) 2005-01-18 US disclosed
US-20030234849-A1 Phase change ink imaging component with MICA-type silicate layer XEROX CORPORATION 2003-12-25 US disclosed
US-20020076540-A1 Transfix component having mica-type silicate outer layer XEROX CORPORATION 2002-06-20 US disclosed
EP-1215540-A2 Transfix component having mica-type silicate outer layer Xerox Corporation (US) 2002-06-19 EP disclosed
US-6014155-A Printing machine with a heated imaging member XEROX CORPORATION (US) 2000-01-11 US disclosed
US-5846643-A Thermally stable fuser member XEROX CORPORATION (US) 1998-12-08 US disclosed
US-5679463-A POLYDIMETHYLSILOXANE ELASTOMER; THERMOCONDUCTIVITY; ELECTROSTATOGRAPHIC FUSING EASTMAN KODAK COMPANY (US) 1997-10-21 US disclosed
US-4925895-A TRANSITION METAL COMPLEX FOR OXIDATION RESISTANCE, FUSER ROLLS IN ELECTROGRAPHIC MACHINES XEROX CORPORATION (US) 1990-05-15 US disclosed
US-4777087-A MIXTURE OF POLYSILOXANE AND COMPLEX OF TRANSITION METAL SALT AND LIGAND XEROX CORPORATION (US) 1988-10-11 US disclosed
EP-0172668-A1 Fuser member for electrostatographic copiers XEROX CORPORATION (US) 1986-02-26 EP disclosed
US-4518655-A HYDROXY ENCAPPED POLYDIMETHYLSILOXANE, ALUMINA, TABULAR ALUMINA, CALCINED ALUMINA, AND CROSSLINKING AGENT AND CATALYST XEROX CORPORATION (US) 1985-05-21 US disclosed
US-4515884-A RELEASE AGENT, XEROGRAPHY XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4373239-A Fusing member for electrostatographic copiers XEROX CORPORATION (US) 1983-02-15 US disclosed
EP-0035362-A1 A thermally conductive fuser member XEROX CORPORATION (US) 1981-09-09 EP disclosed