Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525919 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4EMAPTNPSR1ELANE | |
| SCHEMBL29811263 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4EMAPTNPSR1ELANE | |
| SCHEMBL29811258 | 0.77 | PKM (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL607256 | 0.77 | PKM (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL29811590 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL4822294 | 0.77 | ATM (0.45) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL2384145 | 0.77 | ESR2 (0.41) | ALDH1A1HPGDMAPTSMN1; SMN2CA12 | |
| SCHEMBL29811388 | 0.77 | ATM (0.45) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL22239410 | 0.77 | PDE2A (0.46) | ALDH1A1HPGDNPSR1 | |
| SCHEMBL29811309 | 0.77 | ESR2 (0.41) | ALDH1A1HPGDMAPTSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655543-A | Preparation method of ulcerative colitis treatment medicine | 北京康立生医药技术开发有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-100390148-C | Method for the treatment of malignant tumours | ACTIVE BIOTECH AB (SE) | 2008-05-28 | — | — | CN | disclosed |
| EP-1224172-B1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2007-04-04 | — | — | EP | disclosed |
| CN-1589264-A | Method for the treatment of malignant tumours | ACTIVE BIOTECH AB (SE) | 2005-03-02 | — | — | CN | disclosed |
| US-6605616-B1 | Autoimmune diseases; inflammation | ACTIVE BIOTECH AB (SE) | 2003-08-12 | — | — | US | disclosed |
| EP-1224172-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | Active Biotech AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| US-6395750-B1 | Includes laquinimod, N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxamide and its salts; breat or prostate cancer | ACTIVE BIOTECH AB (SE) | 2002-05-28 | — | — | US | disclosed |
| WO-2001030758-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2001-05-03 | — | — | WO | disclosed |