SCHEMBL5167522

SCHEMBL5167522

Cc1cc(C)c(C(=O)PCC(C)C)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 4/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
TAS1R2 Q8TE23 2/20 0.33
GAA P10253 1/20 0.33
CRHR1 P34998 1/20 0.32
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5997152 0.84 HTR1D (0.34) HPGDKDM4EL3MBTL1ALDH1A1MAPT
SCHEMBL5994814 0.82 MEN1 (0.31) MEN1KMT2AKDM4E
SCHEMBL5997354 0.81 KDM4E (0.32) MEN1KMT2AKDM4EMAPT
SCHEMBL5997139 0.81 L3MBTL1 (0.36) HPGDMEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL5168673 0.80 L3MBTL1 (0.37) HPGDNPSR1MCOLN3MEN1KMT2A
SCHEMBL6429889 0.80 TSHR (0.41) HPGDNPSR1MCOLN3SMN1; SMN2ALDH1A1
SCHEMBL5997147 0.80 ACHE (0.41) MEN1KMT2ASMN1; SMN2KDM4EL3MBTL1
SCHEMBL3870505 0.79 HPGD (0.42) HPGDNPSR1MCOLN3MEN1KMT2A
SCHEMBL27507491 0.78 ACHE (0.40) MEN1KMT2ASMN1; SMN2KDM4EL3MBTL1
SCHEMBL5997368 0.77 TAS1R3 (0.40) HPGDMEN1KMT2ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1628778-B1 STRONGLY ADHERENT SURFACE COATINGS CIBA SC HOLDING AG (CH) 2007-04-18 EP disclosed
US-20060257681-A1 Strongly adherent surface coatings CIBA SPECIALTY CHEMICALS CORP. 2006-11-16 US disclosed
US-7109250-B2 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. (US) 2006-09-19 US disclosed
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
EP-1628778-A1 STRONGLY ADHERENT SURFACE COATINGS Ciba SC Holding AG (CH) 2006-03-01 EP disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-20050004247-A1 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. 2005-01-06 US disclosed
WO-2004103580-A1 STRONGLY ADHERENT SURFACE COATINGS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-12-02 WO disclosed
EP-1446410-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES Ciba SC Holding AG (CH) 2004-08-18 EP disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
WO-2003044030-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-30 WO disclosed
JP-2002069085-A ORGANOMETALLIC MONOACYLALKYLPHOSPHINE CIBA SPECIALTY CHEM HOLDING INC 2002-03-08 JP disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 HPGD 2368/4885NPSR1 715/4885MCOLN3 149/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 HPGD 3137/4885NPSR1 2280/4885MCOLN3 767/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 HPGD 3884/4885NPSR1 505/4885MCOLN3 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.