Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065651 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL1041654 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL733740 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL4727517 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Bicarbonate SCHEMBL9066694 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL335181 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL11128304 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL325376 | 0.83 | PARP10 (0.49) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL1071630 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL2033351 | 0.82 | NPC1 (0.41) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070059692-A1 | Array oligomer synthesis and use | Life Technologies Corporation | 2007-03-15 | — | — | US | disclosed |
| EP-1015420-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999012892-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |
| US-5424057-A | Medical diagnosis | CIBA-GEIGY CORP. (US) | 1995-06-13 | — | — | US | disclosed |
| US-5328992-A | Compounds used as metal chelators and for medical diagnosis | CIBA-GEIGY CORP. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5185368-A | Complex with trivalent metal ions; medical diagnosis and therapy | CIBA-GEIGY CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |