SCHEMBL325376

SCHEMBL325376

NC(=O)OOCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.49
ALDH1A1 P00352 4/20 0.48
LMNA P02545 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 2/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
IDO1 P14902 1/20 0.46
AGXT P21549 1/20 0.45
SLC1A3 P43003 2/20 0.44
SLC1A2 P43004 2/20 0.44
SLC1A1 P43005 2/20 0.44
TSHR P16473 2/20 0.44
MEN1 O00255 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30991497 0.98 AGXT (0.48) PARP10ALDH1A1LMNANPC1RAB9A
SCHEMBL5167833 0.83 ALDH1A1 (0.52) ALDH1A1LMNANPC1RAB9AKMT2A
SCHEMBL1041654 0.83 ALDH1A1 (0.52) ALDH1A1LMNANPC1RAB9AKMT2A
SCHEMBL17289472 0.82 CYP3A4 (0.39) PARP10ALDH1A1LMNARAB9AL3MBTL1
SCHEMBL8986651 0.80 ALDH1A1 (0.48) PARP10ALDH1A1NPC1RAB9AKMT2A
Bicarbonate SCHEMBL9066694 0.80 ALDH1A1 (0.58) ALDH1A1LMNANPC1RAB9AKMT2A
Lysine SCHEMBL21964105 0.80 GSR (0.53) KMT2ATDP1SLC1A3SLC1A2SLC1A1
SCHEMBL1071630 0.79 ALDH1A1 (0.64) ALDH1A1LMNANPC1RAB9AKMT2A
SCHEMBL8687111 0.79 IDO1 (0.46) PARP10ALDH1A1LMNASLC6A2SLC6A3
SCHEMBL11128304 0.79 ALDH1A1 (0.48) ALDH1A1LMNANPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409535-A1 SOLID FORMS OF 3-((1R,3R)-1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)AZETIDIN-3-YL)AMINO)PHENYL)-3-METHYL-1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOL-2-YL)-2,2-DIFLUOROPROPAN-1-OL AND PROCESSES FOR PREPARING FUSED TRICYCLIC COMPOUNDS COMPRISING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY, INCLUDING METHODS OF THEIR USE GENENTECH, INC. (US) 2024-12-12 US claimed
CN-116601163-A Protected disaccharides, methods for their preparation, their use in the synthesis of zwitterionic oligosaccharides and conjugates thereof 巴斯德研究所 2023-08-15 CN claimed
WO-2022238500-A1 RADIOSYNTHESIS OF [18F] TALAZOPARIB EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2022-11-17 WO claimed
EP-4089093-A1 RADIOSYNTHESIS OF [18F] TALAZOPARIB Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) 2022-11-16 EP claimed
US-11084794-B2 Controlled cyclization of peptoids to form chiral diketopiperazines TRIAD NATIONAL SECURITY, LLC (US) 2021-08-10 US claimed
US-11072713-B2 Bugphobic and icephobic compositions with fluid additives HRL LABORATORIES, LLC (US) 2021-07-27 US claimed
EP-3746509-A1 BUGPHOBIC AND ICEPHOBIC COMPOSITIONS WITH FLUID ADDITIVES HRL Laboratories, LLC (US) 2020-12-09 EP claimed
US-20200131140-A1 CONTROLLED CYCLIZATION OF PEPTOIDS TO FORM CHIRAL DIKETOPIPERAZINES TRIAD NATIONAL SECURITY, LLC (US) 2020-04-30 US claimed
WO-2019152081-A1 BUGPHOBIC AND ICEPHOBIC COMPOSITIONS WITH FLUID ADDITIVES HRL LABORATORIES, LLC (US) 2019-08-08 WO claimed
US-20190023910-A1 BUGPHOBIC AND ICEPHOBIC COMPOSITIONS WITH FLUID ADDITIVES HRL LABORATORIES, LLC 2019-01-24 US claimed
WO-2017018835-A1 METHOD OF PREPARING TDM-621 DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2017-02-02 WO claimed
WO-2016043661-A1 MODIFIED PEPTIDE NUCLEIC ACIDS AND THEIR USE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-03-24 WO claimed
WO-2015092739-A1 PROCESS FOR PREPARATION OF ALOGLIPTIN Mylan Laboratories Ltd. (IN) 2015-06-25 WO claimed
CN-101454333-B Lactosamine derivatives GLYCOM AS 2013-08-28 CN claimed
CN-101454333-A Novel lactosamine derivatives GLYCOM APS (DK) 2009-06-10 CN claimed
US-20260137767-A1 LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES VIROMETIX AG (CH) 2026-05-21 US disclosed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
EP-0089165-B1 IMMOBILIZED MICROBIAL CELLS AND PROCESS FOR PREPARING AND USING SAME RHONE-POULENC CHIMIE (FR) 1991-10-09 EP disclosed
US-4732851-A CURING ON CARRIER PURIFICATION ENGINEERING, INC. (US) 1988-03-22 US disclosed
EP-0089165-A2 Immobilized microbial cells and process for preparing and using same RHONE-POULENC CHIMIE (FR) 1983-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137767-A1 LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES VSIR, LRBA, CD74 PARP10 4219/4885ALDH1A1 4871/4885LMNA 275/4885
US-11072713-B2 Bugphobic and icephobic compositions with fluid additives FUS, IGF2BP1, IGF2BP3 PARP10 3043/4885ALDH1A1 3660/4885LMNA 894/4885
US-11084794-B2 Controlled cyclization of peptoids to form chiral diketopiperazines NPPA, NPEPPS, RRP15 PARP10 3222/4885ALDH1A1 4849/4885LMNA 2344/4885
US-20200131140-A1 CONTROLLED CYCLIZATION OF PEPTOIDS TO FORM CHIRAL DIKETOPIPERAZINES NPPA, NPEPPS, RRP15 PARP10 3222/4885ALDH1A1 4849/4885LMNA 2344/4885
US-20240409535-A1 SOLID FORMS OF 3-((1R,3R)-1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)AZETIDIN-3-YL)AMINO)PHENYL)-3-METHYL-1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOL-2-YL)-2,2-DIFLUOROPROPAN-1-OL AND PROCESSES FOR PREPARING FUSED TRICYCLIC COMPOUNDS COMPRISING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY, INCLUDING METHODS OF THEIR USE TP53, DPYD, FLI1 PARP10 1601/4885ALDH1A1 399/4885LMNA 2912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.