Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 3/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909807 | 0.83 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1TDP1MAPK1 | |
| SCHEMBL5167833 | 0.82 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1TDP1MAPK1 | |
| SCHEMBL4441192 | 0.79 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1TDP1MAPK1 | |
| SCHEMBL9065651 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7440434 | 0.76 | HTR2A (0.53) | NPC1RAB9AALDH1A1 | |
| SCHEMBL27471961 | 0.75 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1TDP1MAPK1 | |
| SCHEMBL2963499 | 0.74 | TSHR (0.44) | NPC1RAB9AALDH1A1TDP1MAPK1 | |
| SCHEMBL1041654 | 0.74 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1TDP1MAPK1 | |
| SCHEMBL733740 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL12476191 | 0.74 | ALOX5 (0.39) | ALDH1A1KMT2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953850-B1 | Protecting groups for carbohydrate synthesis | ALCHEMIA PTY. LTD. (AU) | 2005-10-11 | — | — | US | claimed |
| US-20130123486-A1 | Photogenerated reagents | GAO XIAOLIAN (US) | 2013-05-16 | — | — | US | disclosed |
| US-8076501-B2 | Photogenerated reagents | LC SCIENCES LC | 2011-12-13 | — | — | US | disclosed |
| US-20110251109-A1 | Fluidic methods for devices for parallel chemical reactions | Life Technologies Corporation (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110170075-A1 | DEVICE FOR CHEMICAL AND BIOCHEMICAL REACTIONS USING PHOTO-GENERATED REAGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2011-07-14 | — | — | US | disclosed |
| EP-2332645-A1 | Apparatus for chemical and biochemical reactions using photo-generated reagents | THE UNIVERSITY OF HOUSTON (US) | 2011-06-15 | — | — | EP | disclosed |
| US-7838466-B2 | Device for chemical and biochemical reactions using photo-generated reagents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-11-23 | — | — | US | disclosed |
| US-20100137600-A1 | Photogenerated reagents | LC SCIENCES LC | 2010-06-03 | — | — | US | disclosed |
| US-7544829-B2 | Photogenerated reagents | LC SCIENCES LC | 2009-06-09 | — | — | US | disclosed |
| US-7544638-B2 | Device for chemical and biochemical reactions using photo-generated reagents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-06-09 | — | — | US | disclosed |
| US-20030118486-A1 | Fluidic methods and devices for parallel chemical reactions | XEOTRON CORPORATION (US) | 2003-06-26 | — | — | US | disclosed |
| US-20030091476-A1 | Comprises microscopic vessels; for microarrays of DNA and RNA oligonucleotides, peptides, oligosacchrides, and phospholipids; genetic mapping; drug screening | Life Technologies Corporation | 2003-05-15 | — | — | US | disclosed |
| EP-1301268-A2 | DEVICES AND METHODS FOR CARRYING OUT CHEMICAL REACTIONS USING PHOTOGENERATED REAGENTS | Xeotron Corporation (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-1258288-A2 | Method and apparatus for chemical and biochemical reactions using photo-generated reagents | THE UNIVERSITY OF HOUSTON (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6426184-B1 | MAKING MULTIMERS SUCH AS DNA OR PEPTIDES IN CHEMICAL REACTOR BY SOLUTION-BASED PHOTOCHEMICAL REACTIONS INVOLVING REAGENTS GENERATED IN SITU BY IRRADIATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-30 | — | — | US | disclosed |
| US-20020081582-A1 | Making multimers such as DNA or peptides in chemical reactor by solution-based photochemical reactions involving reagents generated in situ by irradiation | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2002-06-27 | — | — | US | disclosed |
| US-20020012616-A1 | Useful for distributing liquids, implementing discrete photochemical reactions for in situ production of reagents, and activating discrete chemical and biochemical reactions | Life Technologies Corporation | 2002-01-31 | — | — | US | disclosed |
| WO-2002002227-A2 | DEVICES AND METHODS FOR CARRYING OUT CHEMICAL REACTIONS USING PHOTOGENERATED REAGENTS | XEOTRON CORPORATION (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-1054726-A2 | METHOD AND APPARATUS FOR CHEMICAL AND BIOCHEMICAL REACTIONS USING PHOTO-GENERATED REAGENTS | THE UNIVERSITY OF HOUSTON (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041007-A2 | METHOD AND APPARATUS FOR CHEMICAL AND BIOCHEMICAL REACTIONS USING PHOTO-GENERATED REAGENTS | UNIVERSITY OF HOUSTON (US) | 1999-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123486-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | NPC1 4639/4885RAB9A 4064/4885ALDH1A1 1813/4885 |
| US-20100137600-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | NPC1 4639/4885RAB9A 4064/4885ALDH1A1 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.