SCHEMBL5167915

SCHEMBL5167915

CCOC(=O)c1ccc2c(=S)c3cc(OC)ccc3oc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.52
ALDH1A1 P00352 8/20 0.52
HPGD P15428 5/20 0.52
PTGS2 P35354 1/20 0.51
TSHR P16473 3/20 0.47
MAOB P27338 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SLC22A12 Q96S37 1/20 0.46
MAPT P10636 3/20 0.46
NPSR1 Q6W5P4 1/20 0.45
NPC1 O15118 1/20 0.45
CASP3 P42574 1/20 0.45
RAB9A P51151 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
GAA P10253 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5166609 0.87 RAB9A (0.46) KDM4EALDH1A1HPGDPTGS2MAOB
SCHEMBL11725164 0.83 KDM4E (0.64) KDM4EALDH1A1HPGDPTGS2TSHR
SCHEMBL1821611 0.82 TNKS (0.56) KDM4EALDH1A1HPGDPTGS2TSHR
SCHEMBL1822187 0.80 ESR1 (0.44) KDM4EALDH1A1HPGDTSHRSMN1; SMN2
SCHEMBL11340464 0.76 HPGD (0.53) KDM4EALDH1A1HPGDMAOBSMN1; SMN2
SCHEMBL5171476 0.74 TTR (0.45) KDM4EALDH1A1HPGDTSHRMAOB
SCHEMBL1473247 0.74 KDM4E (0.69) KDM4EALDH1A1HPGDSMN1; SMN2POLB
SCHEMBL28654740 0.74 PTGS2 (0.85) KDM4EALDH1A1HPGDPTGS2TSHR
SCHEMBL11165496 0.73 ALDH1A1 (0.51) KDM4EALDH1A1HPGDMAOBSMN1; SMN2
SCHEMBL85996 0.73 MAOB (0.62) KDM4EALDH1A1HPGDMAOBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558402-B1 METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES CIBA SC HOLDING AG (CH) 2007-04-18 EP disclosed
EP-1558402-A2 METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES Ciba Specialty Chemicals Holding Inc. (CH) 2005-08-03 EP disclosed
WO-2004035667-A2 METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-29 WO disclosed
EP-1135219-B1 METHOD FOR PRODUCING ADHESIVE SURFACE COATINGS CIBA SC HOLDING AG (CH) 2004-01-28 EP disclosed
EP-1135219-A1 METHOD FOR PRODUCING ADHESIVE SURFACE COATINGS Ciba SC Holding AG (CH) 2001-09-26 EP disclosed
WO-2000024527-A1 METHOD FOR PRODUCING ADHESIVE SURFACE COATINGS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-04 WO disclosed
EP-0138754-B1 PHOTOCURABLE COMPOSITIONS CIBA-GEIGY AG (CH) 1988-05-25 EP disclosed
EP-0138754-A2 Photocurable compositions CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed