Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165358 | 0.92 | CYP2C19 (0.49) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5517831 | 0.91 | MAPT (0.51) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5515197 | 0.89 | TSHR (0.54) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27480820 | 0.85 | TSHR (0.55) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5166992 | 0.80 | KMT2A (0.56) | CYP2C19CYP1A2CYP2C9LMNAMAPT | |
| SCHEMBL5516179 | 0.80 | CYP1A2 (0.43) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27545274 | 0.80 | TSHR (0.55) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5508703 | 0.78 | POLB (0.46) | CYP3A4LMNAMAPTKMT2AMEN1 | |
| SCHEMBL30506315 | 0.77 | HSD17B2 (0.76) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1660365 | 0.77 | HSD17B2 (0.76) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238812-B2 | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents | MEJI SEIKA KAISHA, LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-7238719-B2 | Process for producing 1,2,3-Triazole compounds | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| EP-1471058-B1 | PROCESS FOR PRODUCING 1,2,3-TRIAZOLE COMPOUND | MEIJI SEIKA KAISHA (JP) | 2007-04-11 | — | — | EP | disclosed |
| US-20060074074-A1 | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |
| US-7022860-B2 | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20050080270-A1 | Process for producing 1 2 3 triazole compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1471058-A1 | PROCESS FOR PRODUCING 1,2,3-TRIAZOLE COMPOUND | MEIJI SEIKA KAISHA LTD. (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-1026167-B1 | TRICYCLIC TRIAZOLOBENZAZEPINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND ANTIALLERGIC AGENTS | MEIJI SEIKA KAISHA (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-20020137739-A1 | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2002-09-26 | — | — | US | disclosed |
| US-6372735-B1 | ANTIHISTAMINES | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-1026167-A1 | TRICYCLIC TRIAZOLOBENZAZEPINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND ANTIALLERGIC | MEIJI SEIKA KAISHA LTD. (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080270-A1 | Process for producing 1 2 3 triazole compound | RPS27L, KARS1, STK38L | CYP2C19 30/4885TSHR 718/4885CYP1A2 26/4885 |
| US-20060074074-A1 | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents | HRH4, CYP2D6, CYP2B6 | CYP2C19 10/4885TSHR 489/4885CYP1A2 30/4885 |
| US-20020137739-A1 | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents | HRH4, CYP3A4, TPH1 | CYP2C19 11/4885TSHR 826/4885CYP1A2 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.