Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178818 | 0.91 | PPARG (0.38) | ATMCCR3UTS2RL3MBTL1ALDH1A1 | |
| SCHEMBL5189648 | 0.80 | PTPN1 (0.44) | ATMCCR3UTS2RL3MBTL1ALDH1A1 | |
| SCHEMBL5178812 | 0.76 | PTGDR2 (0.45) | PPIDLMNA | |
| SCHEMBL14450445 | 0.73 | PTPN1 (0.48) | PPARGEPHX2PPARA | |
| SCHEMBL7244978 | 0.73 | PTPN1 (0.46) | ALDH1A1PPARGLMNA | |
| SCHEMBL7244973 | 0.73 | PTPN1 (0.46) | ALDH1A1PPARGLMNA | |
| SCHEMBL3745964 | 0.73 | ITGB3 (0.53) | ALDH1A1 | |
| SCHEMBL3745962 | 0.73 | ITGB3 (0.53) | ALDH1A1 | |
| SCHEMBL2423462 | 0.72 | PTPN1 (0.67) | ALDH1A1MAPTLMNA | |
| SCHEMBL7876107 | 0.72 | PTPN1 (0.67) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765332-A2 | TRISUBSTITUTED NITROGEN MODULATORS OF TYROSINE PHOSPHATASES | Cengent Therapeutics, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006009876-A2 | TRISUBSTITUTED NITROGEN MODULATORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-01-26 | — | — | WO | disclosed |