Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167932 | 0.80 | ATM (0.45) | CCR3ALDH1A1ATMUTS2RL3MBTL1 | |
| SCHEMBL5163594 | 0.76 | PGK1 (0.59) | PTPN1PGK1PGK2PTPRCPTPN2 | |
| SCHEMBL5178818 | 0.74 | PPARG (0.38) | CCR3ALDH1A1ATMUTS2RL3MBTL1 | |
| SCHEMBL4316972 | 0.70 | PTPN1 (0.74) | PTPN1PGK1PGK2PTPRCPTPN2 | |
| SCHEMBL5165050 | 0.69 | PGK1 (0.50) | PTPN1PGK1PGK2PTPRCPTPN2 | |
| SCHEMBL7660739 | 0.69 | PGK1 (0.59) | PTPN1PGK1PGK2PTPRCPTPN2 | |
| SCHEMBL5166585 | 0.68 | PTPN1 (0.55) | PTPN1PGK1PGK2PTPRCPTPN2 | |
| SCHEMBL7890197 | 0.68 | PGK1 (0.51) | PTPN1PGK1PGK2PTPRCPTPN2 | |
| SCHEMBL5163005 | 0.68 | PTPN5 (0.57) | PTPN1PGK1PGK2PTPRCPTPN2 | |
| SCHEMBL7188019 | 0.68 | PGK1 (0.57) | PTPN1PGK1PGK2PTPRCPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765332-A2 | TRISUBSTITUTED NITROGEN MODULATORS OF TYROSINE PHOSPHATASES | Cengent Therapeutics, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006009876-A2 | TRISUBSTITUTED NITROGEN MODULATORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-01-26 | — | — | WO | disclosed |