SCHEMBL5168024

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4798703	0.90	GABRA1 (0.69)	GABRA1GABRB2ALOX5ALOX15ALOX12
	SCHEMBL5164953	0.86	GABRA1 (0.73)	GABRA1GABRB2ALOX5ALOX15ALOX12
	SCHEMBL5164462	0.86	GABRA1 (0.58)	GABRA1GABRB2ALOX5ALOX15ALOX12
	SCHEMBL5167046	0.85	GABRA1 (0.79)	GABRA1GABRB2ALOX5ALOX15ALOX12
	SCHEMBL318750	0.85	GABRA1 (1.00)	GABRA1GABRB2ALOX5ALOX15ALOX12
	SCHEMBL7077803	0.83	GABRA1 (0.51)	GABRA1GABRB2ALOX5ALOX15ALOX12
	SCHEMBL30979255	0.83	GABRA1 (0.69)	GABRA1GABRB2ALOX5ALOX15ALOX12
	SCHEMBL1021086	0.83	ALOX5 (0.71)	GABRA1GABRB2ALOX5ALOX15HIF1A
	SCHEMBL13640498	0.82	GABRA1 (0.50)	GABRA1GABRB2ALOX5ALOX15ALOX12
	SCHEMBL24712454	0.81	GABRA1 (0.79)	GABRA1GABRB2ALOX5ALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.