Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362484 | 0.93 | PTGS2 (0.62) | PTGS2CYP3A4LTA4HPTPN1PTPN11 | |
| SCHEMBL67909 | 0.87 | PTGS2 (0.70) | PTGS2CYP3A4LTA4HPTPN1PTPN11 | |
| SCHEMBL207718 | 0.87 | PTGS2 (0.48) | PTGS2CYP3A4LTA4HGPR84ACHE | |
| SCHEMBL2769207 | 0.87 | CNR1 (0.41) | PTGS2CYP3A4CNR1CNR2GPR84 | |
| SCHEMBL5166224 | 0.86 | PTGS2 (0.69) | PTGS2CYP3A4LTA4HGPR84ESR1 | |
| SCHEMBL5164535 | 0.84 | PTGS2 (0.72) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL69634 | 0.82 | ACHE (0.55) | PTGS2CYP3A4LTA4HACHEALDH1A1 | |
| SCHEMBL16957078 | 0.81 | CNR1 (0.39) | PTGS2CYP3A4PTPN1PTPN11CNR1 | |
| SCHEMBL16527886 | 0.81 | PTGS2 (0.56) | PTGS2CYP3A4LTA4HPTPN1PTPN11 | |
| SCHEMBL3959592 | 0.79 | PTGS2 (0.54) | PTGS2CYP3A4LTA4HPTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817713-B | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-101817713-A | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2010-09-01 | — | — | CN | disclosed |
| WO-2010007114-A2 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010007116-A2 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-21 | — | — | WO | disclosed |
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1633691-B1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| EP-1682473-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF Aktiengesellschaft (DE) | 2006-07-26 | — | — | EP | disclosed |
| CN-1802339-A | Method for producing 2,2'-dihydroxy-biphenyls | BASF AG (DE) | 2006-07-12 | — | — | CN | disclosed |
| EP-1633691-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2005042454-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | disclosed |
| WO-2004108642-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004069779-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | HAO2, DAO, DDO | PTGS2 100/4885CYP3A4 351/4885LTA4H 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.