Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.45 |
| ▸ | ACACA | Q13085 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714704 | 0.91 | ACACB (0.47) | ACACBACACAMEN1PABPC1KMT2A | |
| SCHEMBL3134853 | 0.83 | NPC1 (0.48) | ACACBACACAMEN1PABPC1KMT2A | |
| SCHEMBL3138642 | 0.78 | P2RX3 (0.45) | ACACBOPRM1OPRD1OPRK1P2RX3 | |
| SCHEMBL3147179 | 0.77 | RAB9A (0.49) | ACACBOPRM1OPRD1OPRK1LTA4H | |
| SCHEMBL3142629 | 0.77 | CYP4F2 (0.48) | ACACBACACAOPRM1OPRD1OPRK1 | |
| SCHEMBL3129071 | 0.76 | OXTR (0.41) | ACACBACACAOPRM1OPRD1OPRK1 | |
| SCHEMBL8913031 | 0.74 | CYP4F2 (0.45) | ACACBACACAKCNH2P2RX3 | |
| SCHEMBL3147539 | 0.73 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL3134816 | 0.71 | FFAR1 (0.50) | P2RX3 | |
| SCHEMBL3146690 | 0.71 | CYP4F2 (0.51) | ACACBACACAMEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773797-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014012-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-09 | — | — | WO | disclosed |