Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170874 | 0.79 | OPRM1 (0.39) | GRIN2BRAB9ALMNAGAAMAPT | |
| SCHEMBL7188690 | 0.78 | GRIN2B (0.41) | GRIN2BRAB9ALMNAGAAMAPT | |
| SCHEMBL5169688 | 0.77 | GRIN2B (0.39) | GRIN2BRAB9ALMNAGAAMAPT | |
| SCHEMBL5170803 | 0.77 | OPRM1 (0.39) | GRIN2BRAB9ALMNAGAAMAPT | |
| SCHEMBL5169679 | 0.74 | SLC6A2 (0.44) | GRIN2BRAB9ALMNAGAAMAPT | |
| SCHEMBL5169685 | 0.74 | SLC6A2 (0.44) | GRIN2BRAB9ALMNAGAAMAPT | |
| SCHEMBL5170503 | 0.73 | SLC6A2 (0.46) | GRIN2BOPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL5170791 | 0.73 | SLC6A2 (0.46) | GRIN2BOPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL5168081 | 0.70 | OPRM1 (0.44) | RAB9AMAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL5168065 | 0.65 | SLC6A2 (0.41) | GRIN2BOPRM1OPRD1OPRK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322590-B1 | 5-AMINO-1-PENTENE-3-OL SUBSTITUTED DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-05-02 | — | — | EP | claimed |