Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170874 | 0.97 | OPRM1 (0.39) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5168081 | 0.88 | OPRM1 (0.44) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5170503 | 0.79 | SLC6A2 (0.46) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5170791 | 0.79 | SLC6A2 (0.46) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5169679 | 0.78 | SLC6A2 (0.44) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5169685 | 0.78 | SLC6A2 (0.44) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5169692 | 0.77 | GRIN2B (0.38) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5169688 | 0.76 | GRIN2B (0.39) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5168072 | 0.68 | SLC6A2 (0.41) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL5168065 | 0.68 | SLC6A2 (0.41) | OPRM1OPRD1SLC6A2SLC6A4OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322590-B1 | 5-AMINO-1-PENTENE-3-OL SUBSTITUTED DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-05-02 | — | — | EP | claimed |
| US-6815443-B2 | CARBOCYCLIC OXY AMINES SUCH AS 2-BENZYLIDENE-6-DIMETHYLAMINO METHYLCYCLOHEXANONE, USED AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2004-11-09 | — | — | US | claimed |
| US-20030220390-A1 | 5-Amino-1-pentene-3-ol substituted derivatives | GRUENENTHAL GMBH (DE) | 2003-11-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220390-A1 | 5-Amino-1-pentene-3-ol substituted derivatives | ALOX5, PGA5, ANXA5 | OPRM1 294/4885OPRD1 211/4885SLC6A2 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.