Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169692 | 0.78 | GRIN2B (0.38) | GRIN2BOPRM1OPRD1HTR2AHTR2C | |
| SCHEMBL7188687 | 0.75 | GRIN2B (0.40) | GRIN2BOPRM1OPRD1HTR2AHTR2C | |
| SCHEMBL4374265 | 0.72 | SLC6A2 (0.46) | GRIN2BOPRM1OPRD1HTR2AHTR2C | |
| SCHEMBL4664156 | 0.64 | GRIN2B (0.40) | GRIN2BOPRM1OPRD1HTR2AHTR2C | |
| SCHEMBL5169688 | 0.64 | GRIN2B (0.39) | GRIN2BOPRM1OPRD1HTR2AHTR2C | |
| SCHEMBL4663525 | 0.62 | OPRK1 (0.49) | OPRM1OPRD1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL29573736 | 0.61 | MAPT (0.52) | SLC6A3LMNAGAAMAPTRAB9A | |
| SCHEMBL1043138 | 0.61 | MAPT (0.52) | SLC6A3LMNAGAAMAPTRAB9A | |
| SCHEMBL5170874 | 0.61 | OPRM1 (0.39) | GRIN2BOPRM1OPRD1HTR2AHTR2C | |
| SCHEMBL13698140 | 0.60 | CCR2 (0.47) | OPRM1OPRD1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216393-A1 | Substituted 1-aminobutan-3-ol compounds | GRUENENTHAL GMBH (DE) | 2003-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216393-A1 | Substituted 1-aminobutan-3-ol compounds | CYP3A43, UGT1A3, UGT2B7 | GRIN2B 963/4885OPRM1 118/4885OPRD1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.