Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | ESRRA | P11474 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5171820 | 0.84 | HTR7 (0.55) | HTR7LMNAGLATNFSF11TNF | |
| SCHEMBL13335070 | 0.78 | SCN9A (0.60) | HTR7ESRRA | |
| Hydrochloric Acid SCHEMBL15769689 | 0.77 | TNF (0.76) | HTR7TNFSF11TNF | |
| SCHEMBL5961922 | 0.76 | LMNA (0.69) | LMNAGLA | |
| SCHEMBL11893357 | 0.76 | CACNB4 (0.72) | LMNA | |
| SCHEMBL5172146 | 0.76 | RORC (0.58) | HTR7TNFSF11TNF | |
| Hydrochloric Acid SCHEMBL28233643 | 0.76 | HTR7 (0.60) | HTR7LMNAGLATNFESRRA | |
| SCHEMBL31370506 | 0.75 | HTR7 (0.50) | HTR7ESRRA | |
| SCHEMBL12260524 | 0.75 | HTR7 (0.50) | HTR7ESRRA | |
| SCHEMBL1881313 | 0.75 | HTR7 (0.56) | HTR7ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |