Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethoxyethanol SCHEMBL11438258 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TSHRTHRBHSD17B10LMNA | |
| Ether SCHEMBL4013610 | 0.89 | ALDH1A1 (0.60) | ALDH1A1TSHRTHRBMAPK1PPARD | |
| 2-Methoxyethanol SCHEMBL4002512 | 0.89 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| Ether SCHEMBL271068 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBHSD17B10LMNA | |
| Ether SCHEMBL151167 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBHSD17B10LMNA | |
| 2-Methoxyethanol SCHEMBL1357144 | 0.86 | — | — | |
| Ether SCHEMBL702338 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TSHRTHRBMAPK1PPARD | |
| Ether SCHEMBL953110 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRTHRBHSD17B10LMNA | |
| Di(Hydroxyethyl)Ether SCHEMBL5071580 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TSHRTHRBHSD17B10LMNA | |
| Ether SCHEMBL9151602 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRBHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070990-B1 | Lithographic printing plate precursor and method of making lithographic printing plate | FUJIFILM CORP (JP) | 2007-04-25 | — | — | EP | disclosed |
| EP-1070990-A1 | Photosensitive composition and method of making lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |