Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL382184 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNAHSD17B10FFAR3 | |
| Ether SCHEMBL5962169 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNAHSD17B10FFAR3 | |
| Ether SCHEMBL151167 | 0.97 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAHSD17B10FFAR3 | |
| Ether SCHEMBL271068 | 0.97 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAHSD17B10FFAR3 | |
| Ether SCHEMBL5597101 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAHSD17B10FFAR3 | |
| Ether SCHEMBL7763625 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAHSD17B10FFAR3 | |
| Ether SCHEMBL7559335 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAHSD17B10FFAR3 | |
| Ether SCHEMBL1492008 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNAHSD17B10FFAR3 | |
| Ether SCHEMBL1417335 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAHSD17B10THRB | |
| Ether SCHEMBL20338904 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAHSD17B10FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407979-B1 | A method for processing silver halide photosensitive materials | FUJI PHOTO FILM CO LTD (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5009983-A | Reducing contact with air to prevent plugging of the membrane | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| EP-0407979-A1 | A method for processing silver halide photosensitive materials | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-16 | — | — | EP | disclosed |