Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | GGH | Q92820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16868468 | 0.88 | CA14 (0.49) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL8081387 | 0.78 | CA9 (0.52) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL3068557 | 0.78 | CA2 (0.59) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL195068 | 0.78 | CA9 (0.52) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL13043277 | 0.76 | KDM4E (0.48) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL9328080 | 0.76 | CA9 (0.50) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL16868500 | 0.76 | KCNA5 (0.59) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL5169942 | 0.74 | KDM4E (0.47) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL8632209 | 0.74 | NPSR1 (0.50) | CA2CA4CA5ACA12CA9 | |
| SCHEMBL6831560 | 0.74 | CA9 (0.48) | CA2CA4CA5ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761944-A | A kind of chrysin amide derivatives and preparation method thereof and medical usage | 武汉翼博济生生物科技有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-108963389-A | It is a kind of for lithium-air battery can gelling system and its preparation method and application | 北京师范大学 | 2018-12-07 | — | — | CN | claimed |
| EP-0946183-B1 | USE OF PYRIDAZINONE OR PHOSPHINE OXIDE COMPOUNDS TO TREAT OR PREVENT CARDIAC ARRHYTHMIA | MERCK & CO INC (US) | 2007-05-02 | — | — | EP | claimed |
| EP-0946183-A4 | METHODS OF TREATING OR PREVENTING CARDIAC ARRHYTHMIA | MERCK & CO INC (US) | 2001-07-18 | — | — | EP | claimed |
| JP-2001503413-A | — | — | 2001-03-13 | — | — | JP | claimed |
| EP-0946183-A1 | METHODS OF TREATING OR PREVENTING CARDIAC ARRHYTHMIA | Merck & Co., Inc. (US) | 1999-10-06 | — | — | EP | claimed |
| US-5935945-A | ADMINISTERING PHOSPHINE OXIDE COMPOUND WHICH BLOCKS RAPIDLY ACTIVATING DELAYED RECTIFIER POTASSIUM ION CURRENT OF THE ATRIUM | MERCK & CO., INC. (US) | 1999-08-10 | — | — | US | claimed |
| WO-1998018476-A1 | METHODS OF TREATING OR PREVENTING CARDIAC ARRHYTHMIA | MERCK & CO., INC. (US) | 1998-05-07 | — | — | WO | claimed |
| CN-100364493-B9 | Water absorbing agent and preparation method thereof, absorber and absorbent commodity using the water absorbing agent | SDP GLOBAL Co.,Ltd. (JP) | 2019-11-08 | — | — | CN | disclosed |
| CN-106165175-B | High molecular electrolyte composition and polyelectrolyte membrane, film electrode composite element and the polymer electrolyte fuel cell for using it | 东丽株式会社 | 2019-11-08 | — | — | CN | disclosed |
| CN-109983128-A | Oligonucleotide composition and its method | 波涛生命科学有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109761944-A | A kind of chrysin amide derivatives and preparation method thereof and medical usage | 武汉翼博济生生物科技有限公司 | 2019-05-17 | — | — | CN | disclosed |
| CN-108963389-A | It is a kind of for lithium-air battery can gelling system and its preparation method and application | 北京师范大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-108962627-A | A kind of supercapacitor or capacitor batteries of organic system | 北京师范大学 | 2018-12-07 | — | — | CN | disclosed |
| EP-0946183-A4 | METHODS OF TREATING OR PREVENTING CARDIAC ARRHYTHMIA | MERCK & CO INC (US) | 2001-07-18 | — | — | EP | disclosed |
| US-6214809-B1 | ANTIARRTHYMIA AGENTS | MERCK & CO., INC. | 2001-04-10 | — | — | US | disclosed |
| EP-0946183-A1 | METHODS OF TREATING OR PREVENTING CARDIAC ARRHYTHMIA | Merck & Co., Inc. (US) | 1999-10-06 | — | — | EP | disclosed |
| US-5935945-A | ADMINISTERING PHOSPHINE OXIDE COMPOUND WHICH BLOCKS RAPIDLY ACTIVATING DELAYED RECTIFIER POTASSIUM ION CURRENT OF THE ATRIUM | MERCK & CO., INC. (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1998018476-A1 | METHODS OF TREATING OR PREVENTING CARDIAC ARRHYTHMIA | MERCK & CO., INC. (US) | 1998-05-07 | — | — | WO | disclosed |
| CN-1102648-A | Substituted mono- and bipyridylmethylpyridenes | BAYER AG (DE) | 1995-05-17 | — | — | CN | disclosed |