SCHEMBL516995

SCHEMBL516995

CN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.63
CASP3 P42574 1/20 0.63
CASP4 P49662 1/20 0.63
CASP7 P55210 1/20 0.63
CASP9 P55211 1/20 0.63
CASP6 P55212 1/20 0.63
NR1H2 P55055 1/20 0.61
NR1H3 Q13133 1/20 0.61
PTPRC P08575 3/20 0.58
S100A4 P26447 2/20 0.58
CYP3A4 P08684 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ALDH1A1 P00352 3/20 0.57
ALOX5 P09917 1/20 0.55
MAPT P10636 1/20 0.55
ACHE P22303 2/20 0.55
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29945629 1.00 CASP1 (0.63) CASP1CASP3CASP4CASP7CASP9
Phthalimide SCHEMBL27559674 0.88 CYP3A4 (0.67) CASP1CASP3CASP4CASP7CASP9
SCHEMBL8364014 0.86 NR1H2 (0.63) CASP1CASP3CASP4CASP7CASP9
SCHEMBL27559675 0.85 CYP3A4 (0.71) CASP1CASP3CASP4CASP7CASP9
SCHEMBL31268227 0.84 CASP1 (0.54) CASP1CASP3CASP4CASP7CASP9
SCHEMBL617807 0.82 POLB (0.67) CASP1CASP3CASP4CASP7CASP9
SCHEMBL8090142 0.82 ACHE (0.62) ALDH1A1ALOX5ACHECA12CA9
SCHEMBL1704508 0.81 PTPRC (0.58) CASP1CASP3CASP4CASP7CASP9
SCHEMBL3202418 0.81 PTPRC (0.58) CASP1CASP3CASP4CASP7CASP9
SCHEMBL16702921 0.81 PTPRC (0.58) CASP1CASP3CASP4CASP7CASP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798138-A N-methyl-4-amino phthalimide and preparation method thereof 浙江闰土股份有限公司 2025-04-11 CN claimed
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN claimed
CN-119327490-A Solid alkali KF/gamma-Al2O3Preparation method and application of catalyst 河北工业大学 2025-01-21 CN claimed
CN-119118972-A Synthesis method of 2, 3',4' -diphenyl ether tetracarboxylic dianhydride 江苏尚莱特医药化工材料有限公司 2024-12-13 CN claimed
CN-119098120-A Synthesis system and process for 4-nitro-N-methylphthalimide 大连微凯化学有限公司 2024-12-10 CN claimed
CN-118221567-A Method for synthesizing N-alkyl-4-nitrophthalimide by multistage series-parallel gas-liquid microreactor 常州大学 2024-06-21 CN claimed
CN-118221568-A Method for preparing N-alkyl-4-nitrophthalimide by multistage series-parallel microreactors 常州大学 2024-06-21 CN claimed
CN-113549001-B Preparation method of N-alkyl-4-nitrophthalimide 华阳新材料科技集团有限公司 2024-03-22 CN claimed
CN-115780487-B Extractant and method for treating solid waste in 4,4' -diphenyl ether dianhydride production by using extractant 河北东丽新材料有限公司 2023-05-05 CN claimed
CN-115780487-A Extracting agent and method for treating solid waste in 4,4' -diphenyl ether dianhydride production by using same 河北东丽新材料有限公司 2023-03-14 CN claimed
US-4476309-A Method for making aromatic etherimides GENERAL ELECTRIC COMPANY (US) 1984-10-09 US claimed
US-4455431-A Method for making bis-etherphthalimides GENERAL ELECTRIC COMPANY (US) 1984-06-19 US claimed
EP-0108682-A1 Solvent free preparation of diarylthioethers GENERAL ELECTRIC COMPANY (US) 1984-05-16 EP claimed
US-4273712-A PHASE TRANSFER CATALYSTS GENERAL ELECTRIC COMPANY (US) 1981-06-16 US claimed
US-4257953-A Method for making bisphenoxide salts and bisimides derived therefrom GENERAL ELECTRIC COMPANY (US) 1981-03-24 US claimed
US-4054577-A Preparation of aromatic bisimides GENERAL ELECTRIC COMPANY (US) 1977-10-18 US claimed
US-4017511-A Preparation of aromatic bisimides GENERAL ELECTRIC COMPANY (US) 1977-04-12 US claimed
US-4005102-A METHYLENE CHLORIDE, NITRIC AND SULFURIC ACIDS GENERAL ELECTRIC COMPANY (US) 1977-01-25 US claimed
US-3992406-A Preparation of aromatic bisimides GENERAL ELECTRIC COMPANY (US) 1976-11-16 US claimed
US-3933852-A Process for making N-methyl nitrophthalimides GENERAL ELECTRIC COMPANY (US) 1976-01-20 US claimed