SCHEMBL8090142

SCHEMBL8090142

CCCN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.62
ALOX5 P09917 1/20 0.59
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA9 Q16790 2/20 0.59
CA4 P22748 1/20 0.59
RPS6KA2 Q15349 1/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ALDH1A1 P00352 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1569306 0.91 ACHE (0.60) ACHEALOX5CA12CA1CA2
SCHEMBL13202235 0.90 ACHE (0.58) ACHEALOX5CA12CA1CA2
SCHEMBL1573660 0.88 ACHE (0.57) ACHEALOX5CA12CA1CA2
SCHEMBL8095237 0.88 ACHE (0.57) ACHEALOX5CA12CA1CA2
SCHEMBL13202079 0.88 ACHE (0.57) ACHEALOX5CA12CA1CA2
SCHEMBL30070354 0.87 ALOX5 (0.62) ACHEALOX5CA12CA1CA2
SCHEMBL6207633 0.87 ALOX5 (0.62) ACHEALOX5CA12CA1CA2
SCHEMBL3586091 0.84 POLB (0.62) ACHEALOX5CA12CA1CA2
SCHEMBL212527 0.84 PABPC1 (0.64) ACHEALOX5CA12CA1CA2
SCHEMBL6920990 0.84 ACHE (0.58) ACHEALOX5CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0560447-B1 Thermoplastic composition based on polyphenylene ether and polyamide ENICHEM SPA (IT) 1998-05-13 EP claimed
EP-0534543-B1 Polyphenylene ether containing reactive end groups, process for preparing it and relevant thermoplastic compositions ENICHEM SPA (IT) 1997-12-17 EP claimed
EP-0560447-A1 Thermoplastic composition based on polyphenylene ether and polyamide ENICHEM S.p.A. (IT) 1993-09-15 EP claimed
EP-0534543-A1 Polyphenylene ether containing reactive end groups, process for preparing it and relevant thermoplastic compositions ENICHEM S.p.A. (IT) 1993-03-31 EP claimed
CN-113549001-B Preparation method of N-alkyl-4-nitrophthalimide 华阳新材料科技集团有限公司 2024-03-22 CN disclosed
CN-1073993-C Process for preparing bis (ether anhydrides) using alkylamine derived bismides having low melting temperatures GEN ELECTRIC (US) 2001-10-31 CN disclosed
EP-1059291-A2 Process for preparing bis(ether anhydrides) GENERAL ELECTRIC COMPANY (US) 2000-12-13 EP disclosed
US-6008374-A REACTING N-ALKYL NITROPHTHALIMIDE AND A BISPHENOL ALKALI METAL SALT TO FORM BISIMIDE, EXTRACTING THE FORMED BISIMIDE GENERAL ELECTRIC COMPANY (US) 1999-12-28 US disclosed
US-5936099-A N-ALKYL PHTHALAMIDES BY REACTING LIQUID (C3-C6)ALKYLAMINES AND PHTHALIC ANHYDRIDE; NITRATION FOLLOWED BY REACTING WITH A BISPHENOL A; EXCHANGE REACTION TO FORM DIANHYDRIDE; HYDROLYSIS TO PRODUCE TETRACID MONOMER FOR POLYETHERIMIDES GENERAL ELECTRIC CO. (US) 1999-08-10 US disclosed
EP-0560447-B1 Thermoplastic composition based on polyphenylene ether and polyamide ENICHEM SPA (IT) 1998-05-13 EP disclosed
US-5719295-A FROM N-ALKYL NITROPHTHALAMIDE GENERAL ELECTRIC COMPANY (US) 1998-02-17 US disclosed
EP-0534543-B1 Polyphenylene ether containing reactive end groups, process for preparing it and relevant thermoplastic compositions ENICHEM SPA (IT) 1997-12-17 EP disclosed
CN-1121514-A Process for preparing bis (ether anhydrides) using alkylamine derived bismides having low melting temperatures GEN ELECTRIC (US) 1996-05-01 CN disclosed
EP-0684232-A1 Process for preparing bis(ether anhydrides) GENERAL ELECTRIC COMPANY (US) 1995-11-29 EP disclosed
EP-0560447-A1 Thermoplastic composition based on polyphenylene ether and polyamide ENICHEM S.p.A. (IT) 1993-09-15 EP disclosed
EP-0534543-A1 Polyphenylene ether containing reactive end groups, process for preparing it and relevant thermoplastic compositions ENICHEM S.p.A. (IT) 1993-03-31 EP disclosed