Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 10/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BTD | P43251 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197786 | 0.89 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3VNN1LMNA | |
| SCHEMBL5197021 | 0.89 | AKR1C3 (0.34) | SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL5191421 | 0.89 | HDAC3 (0.39) | SLC6A2SLC6A4SLC6A3HDAC4LMNA | |
| SCHEMBL5171686 | 0.88 | SLC6A2 (0.35) | SLC6A2SLC6A3 | |
| SCHEMBL5172265 | 0.86 | AKR1C3 (0.39) | SLC6A2SLC6A4SLC6A3HDAC4MEF2D | |
| SCHEMBL5171643 | 0.86 | HDAC4 (0.34) | SLC6A2SLC6A4SLC6A3HDAC4MEF2D | |
| SCHEMBL5172609 | 0.84 | GCK (0.42) | HDAC4MEF2DFFAR1FFAR4 | |
| SCHEMBL5168837 | 0.84 | TYRO3 (0.36) | ESR1 | |
| SCHEMBL5169133 | 0.83 | ALDH1A1 (0.35) | — | |
| SCHEMBL5197780 | 0.83 | HDAC3 (0.38) | SLC6A2SLC6A4SLC6A3HDAC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776357-A1 | HYDROXYAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF HISTONE DEACETYLASE (HDAC) | Astellas Pharma Inc. (JP) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016680-A1 | HYDROXYAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF HISTONE DEACETYLASE (HDAC) | ASTELLAS PHARMA INC. (JP) | 2006-02-16 | — | — | WO | disclosed |