Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197780 | 0.90 | HDAC3 (0.38) | ALDH1A1 | |
| SCHEMBL5171832 | 0.89 | RAB9A (0.31) | ALDH1A1TAAR1 | |
| SCHEMBL5197786 | 0.85 | SLC6A2 (0.36) | ALDH1A1SSTR1SSTR4CA2CA5A | |
| SCHEMBL5197021 | 0.85 | AKR1C3 (0.34) | ALDH1A1 | |
| SCHEMBL5191421 | 0.84 | HDAC3 (0.39) | ALDH1A1HCAR2 | |
| SCHEMBL5171686 | 0.84 | SLC6A2 (0.35) | HCAR2CA2CA5ACA9 | |
| SCHEMBL5169616 | 0.84 | MAPKAPK2 (0.31) | ALDH1A1 | |
| SCHEMBL5167688 | 0.84 | AKR1C3 (0.32) | ALDH1A1 | |
| SCHEMBL5195227 | 0.83 | RAB9A (0.32) | TAAR1CA2CA5ACA9GAA | |
| SCHEMBL5170203 | 0.83 | SLC6A2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776357-A1 | HYDROXYAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF HISTONE DEACETYLASE (HDAC) | Astellas Pharma Inc. (JP) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016680-A1 | HYDROXYAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF HISTONE DEACETYLASE (HDAC) | ASTELLAS PHARMA INC. (JP) | 2006-02-16 | — | — | WO | disclosed |